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776-41-0 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Nuclear receptor subfamily 4 group A member 2
External ID: CHEMBL4840093
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2021
Volume: 64
Issue: 20.0
First Page: 15126
Last Page: 15140
DOI: 10.1021/acs.jmedchem.1c01077

Target ChEMBL ID: CHEMBL5002
ChEMBL Target Name: Nuclear receptor subfamily 4 group A member 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
48IC50=48000nM
IC50Not Active
IC50Not Active
3.8IC50=3800nM
53IC50=53000nM
11IC50=11000nM
9IC50=9000nM
1.5IC50=1500nM
24IC50=24000nM
IC50Not Active
2.5IC50=2500nM
IC50Not Active
IC50Not Active
57IC50=57000nM
IC50Not Active
19IC50=19000nM
5IC50=5000nM
20IC50=20000nM
23IC50=23000nM
IC50Not Active