HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Angiotensin-converting enzyme

External ID: CHEMBL648337

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1993
Volume: 36
Issue: 16
First Page: 2390
Last Page: 2403
DOI: 10.1021/jm00068a017

Target ChEMBL ID: CHEMBL1808
ChEMBL Target Name: Angiotensin-converting enzyme
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
0.01202	IC50	=	12.02	nM
229.087	IC50	=	229086.77	nM	Outside typical range
5.248E-4	IC50	=	0.5248	nM
0.001905	IC50	=	1.905	nM
1.318E-4	IC50	=	0.1318	nM
0.001202	IC50	=	1.202	nM
1348.96	IC50	=	1348962.88	nM	Outside typical range
537.032	IC50	=	537031.8	nM	Outside typical range
0.001	IC50	=	1	nM
549.541	IC50	=	549540.87	nM	Outside typical range
1000	IC50	>	1000000	nM	Outside typical range
2.81838	IC50	=	2818.38	nM
0.002884	IC50	=	2.884	nM
47.863	IC50	=	47863.01	nM
77.6247	IC50	=	77624.71	nM
0.001096	IC50	=	1.096	nM
446.684	IC50	=	446683.59	nM	Outside typical range
0.06457	IC50	=	64.57	nM
0.36308	IC50	=	363.08	nM
1819.7	IC50	=	1819700.86	nM	Outside typical range

76166-63-7 靶点实验数据