HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Epidermal growth factor receptor

External ID: CHEMBL680021

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1996
Volume: 39
Issue: 9
First Page: 1823
Last Page: 1835
DOI: 10.1021/jm9508651

Target ChEMBL ID: CHEMBL203
ChEMBL Target Name: Epidermal growth factor receptor erbB1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
6.0E-6	IC50	=	0.006	nM	Outside typical range
0.0023	IC50	=	2.3	nM
0.0026	IC50	=	2.6	nM
0.011	IC50	=	11	nM
0.0031	IC50	=	3.1	nM
0.0096	IC50	=	9.6	nM
0.124	IC50	=	124	nM
0.051	IC50	=	51	nM
2.03	IC50	=	2030	nM
0.052	IC50	=	52	nM
0.013	IC50	=	13	nM
0.263	IC50	=	263	nM
0.324	IC50	=	324	nM
0.034	IC50	=	34	nM
0.03	IC50	=	30	nM
0.035	IC50	=	35	nM
0.01	IC50	=	10	nM
0.029	IC50	=	29	nM
0.578	IC50	=	578	nM
0.009	IC50	=	9	nM

7556-92-5 靶点实验数据