HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Trypanosoma cruzi

External ID: CHEMBL978459

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2006
Volume: 69
Issue: 10
First Page: 1379
Last Page: 1383
DOI: 10.1021/np060007f

Target ChEMBL ID: CHEMBL368
ChEMBL Target Name: Trypanosoma cruzi
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment	Data Validity Comment
	IC50				Not Determined
50	IC50	>	50000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：Shanghai Institute of Organic Chemistry 靶标：N/A

External ID: PDBbind-Kd for protein-ligand complexes

Protocol:

Comment:

PDBbind Data Link	Affinity_Quilifier	Kd	PubMed	Protein Target	Protein Name	MMDB	PDB
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1a1e	=	1	9174343	1A1E_B	tyrosine kinase C-src	73432	1A1E
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1a7c	<=	100	9634700	1A7C_A	plasminogen activator inhibitor type 1	97714	1A7C
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1adl	=	4.4	7929228	1ADL_A	trp rna-binding attenuation protein	55147	1ADL
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ado	=	1	8989320	1ADO_A	fructose 1,6-bisphosphate aldolase	6825	1ADO
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1af6	=	15000	9299337	1AF6_A,1AF6_B	maltoporin	7612	1AF6
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ag9	=	0.001	9416602	1AG9_A	flavodoxin	6827	1AG9
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ahx	=	120	7664122	1AHX_A,1AHX_B	aspartate aminotransferase	3769	1AHX
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ahy	=	440	7664122	1AHY_A,1AHY_B	aspartate aminotransferase	3768	1AHY
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aj6	=	1.2	9245398	1AJ6_A	DNA gyrase b	55222	1AJ6
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aj7	=	135	9180069	1AJ7_L,1AJ7_H	immunoglobulin 48g7 germline fab	6588	1AJ7
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akq	=	7.9E-4	9874201	1AKQ_A	flavodoxin	55243	1AKQ
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akr	=	8.2E-4	9622492	1AKR_A	flavodoxin	55244	1AKR
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akt	=	0.0032	9622492	1AKT_A	flavodoxin	55245	1AKT
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aku	=	0.746		1AKU_A	flavodoxin	55246	1AKU
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akv	=	2.6E-6		1AKV_A	flavodoxin	55247	1AKV
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akw	=	0.0026	9622492	1AKW_A	flavodoxin	55248	1AKW
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1amw	=	29	9230303	1AMW_A	heat shock protein 90	55278	1AMW
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ao0	=	11	9271502	1AO0_A,1AO0_B	glutamine phosphoribosylpyrophosphate	6600	1AO0
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1apb	=	1.51	2204627	1APB_A	apolipoprotein	55308	1APB
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aqi	=	2.4	8995524	1AQI_A	adenine-n6-dna-methyltransferase taqi	5182	1AQI

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Plasmodium falciparum

External ID: CHEMBL978458

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2006
Volume: 69
Issue: 10
First Page: 1379
Last Page: 1383
DOI: 10.1021/np060007f

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
47	IC50	=	47000	nM
50	IC50	>	50000	nM
72	IC50	=	72000	nM
45	IC50	=	45000	nM
29	IC50	=	29000	nM
64	IC50	=	64000	nM
24	IC50	=	24000	nM

7296-55-1 靶点实验数据