HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader -
7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源：ChEMBL靶标：Bile acid receptor
External ID: CHEMBL4040778
Protocol:
N/A
Comment:
Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.
Journal: J Med Chem Year: 2017 Volume: 60 Issue: 16 First Page: 7199 Last Page: 7205 DOI: 10.1021/acs.jmedchem.7b00903
Target ChEMBL ID: CHEMBL2047 ChEMBL Target Name: Bile acid receptor FXR ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain Relationship Type: D - Direct protein target assigned Confidence: Direct single protein target assigned
PubChem Standard Value
Standard Type
Standard Relation
Standard Value
Standard Units
Activity Comment
0.52
EC50
=
520
nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader -
7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源：ChEMBL靶标：Bile acid receptor
External ID: CHEMBL4040779
Protocol:
N/A
Comment:
Journal: J Med Chem Year: 2017 Volume: 60 Issue: 16 First Page: 7199 Last Page: 7205 DOI: 10.1021/acs.jmedchem.7b00903
Target ChEMBL ID: CHEMBL2047 ChEMBL Target Name: Bile acid receptor FXR ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain Relationship Type: D - Direct protein target assigned Confidence: Direct single protein target assigned