HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：DNA topoisomerase 3

External ID: CHEMBL872486

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1980
Volume: 23
Issue: 1
First Page: 34
Last Page: 38
DOI: 10.1021/jm00175a007

Target ChEMBL ID: CHEMBL4320
ChEMBL Target Name: DNA topoisomerase III
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
460	Ki	=	460000	nM	Outside typical range
464	Ki	=	464000	nM	Outside typical range
122	Ki	=	122000	nM	Outside typical range
452	Ki	=	452000	nM	Outside typical range
120	Ki	=	120000	nM	Outside typical range
1770	Ki	=	1770000	nM	Outside typical range
3200	Ki	=	3200000	nM	Outside typical range
413	Ki	=	413000	nM	Outside typical range
17.5	Ki	=	17500	nM
101	Ki	=	101000	nM	Outside typical range
7.6	Ki	=	7600	nM
78.5	Ki	=	78500	nM
0.26	Ki	=	260	nM
0.92	Ki	=	920	nM
31.6	Ki	=	31600	nM
0.63	Ki	=	630	nM
0.42	Ki	=	420	nM
25	Ki	=	25000	nM
19	Ki	=	19000	nM
65.7	Ki	=	65700	nM

72255-75-5 靶点实验数据