HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4035688

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 13
First Page: 2982
Last Page: 2985
DOI: 10.1016/j.bmcl.2017.05.005

Standard Type	Standard Relation	Standard Value
Selectivity Index	=	8.2
Selectivity Index	=	2.5

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4035689

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 13
First Page: 2982
Last Page: 2985
DOI: 10.1016/j.bmcl.2017.05.005

Standard Type	Standard Relation	Standard Value
Selectivity Index	=	7.4
Selectivity Index	=	5.8

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：11-beta-hydroxysteroid dehydrogenase 1

External ID: CHEMBL4035686

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 13
First Page: 2982
Last Page: 2985
DOI: 10.1016/j.bmcl.2017.05.005

Target ChEMBL ID: CHEMBL4235
ChEMBL Target Name: 11-beta-hydroxysteroid dehydrogenase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	37	%
Activity	=	5	%
Activity	=	35	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：11-beta-hydroxysteroid dehydrogenase type 2

External ID: CHEMBL4035687

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 13
First Page: 2982
Last Page: 2985
DOI: 10.1016/j.bmcl.2017.05.005

Target ChEMBL ID: CHEMBL3746
ChEMBL Target Name: 11-beta-hydroxysteroid dehydrogenase 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	83	%
Activity	=	7	%
Activity	=	7	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：17-beta-hydroxysteroid dehydrogenase type 1

External ID: CHEMBL4035685

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 13
First Page: 2982
Last Page: 2985
DOI: 10.1016/j.bmcl.2017.05.005

Target ChEMBL ID: CHEMBL3181
ChEMBL Target Name: Estradiol 17-beta-dehydrogenase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	11	%
Activity	=	41	%
Activity	=	15	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：17-beta-hydroxysteroid dehydrogenase type 2

External ID: CHEMBL4035683

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 13
First Page: 2982
Last Page: 2985
DOI: 10.1016/j.bmcl.2017.05.005

Target ChEMBL ID: CHEMBL2789
ChEMBL Target Name: Estradiol 17-beta-dehydrogenase 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	5	%
Activity	=	10	%
Activity	=	6	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4035690

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 13
First Page: 2982
Last Page: 2985
DOI: 10.1016/j.bmcl.2017.05.005

Standard Type	Standard Relation	Standard Value
Selectivity Index	=	16.6
Selectivity Index	=	1.2

720675-67-2 靶点实验数据