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712-29-8 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Nitric oxide synthase, brain
External ID: CHEMBL751278
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2002
Volume: 45
Issue: 14
First Page: 2923
Last Page: 2941
DOI: 10.1021/jm020074g

Target ChEMBL ID: CHEMBL3568
ChEMBL Target Name: Nitric-oxide synthase, brain
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
88IC50=88000nM
60IC50=60000nM
30IC50=30000nM
172IC50=172000nMOutside typical range
8IC50=8000nM
6IC50=6000nM
42IC50=42000nM
39IC50=39000nM
40IC50=40000nM
2IC50=2000nM