HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL738589

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1980
Volume: 23
Issue: 1
First Page: 13
Last Page: 20
DOI: 10.1021/jm00175a004

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
LD50	=	24.3	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	=	400	mg.kg-1
LD50	=	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	=	40	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1
LD50	>	1000	mg.kg-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Rattus norvegicus

External ID: CHEMBL793205

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1980
Volume: 23
Issue: 1
First Page: 13
Last Page: 20
DOI: 10.1021/jm00175a004

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	68	%
Inhibition	=	28	%
Inhibition	=	24	%
Inhibition	=	42	%
Inhibition	=	32	%
Inhibition	=	46	%
Inhibition	=	9	%
Inhibition	=	32	%
Inhibition	=	62	%
Inhibition	=	57	%
Inhibition	=	57	%
Inhibition	=	36	%
Inhibition	=	36	%
Inhibition	=	34	%
Inhibition	=	73	%
Inhibition	=	42	%
Inhibition	=	40	%
Inhibition	=	39	%
Inhibition	=	19	%
Inhibition	=	33	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Prostaglandin G/H synthase 1

External ID: CHEMBL767954

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1980
Volume: 23
Issue: 1
First Page: 13
Last Page: 20
DOI: 10.1021/jm00175a004

Target ChEMBL ID: CHEMBL2096674
ChEMBL Target Name: Cyclooxygenase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	100	%
Inhibition	=	75.4	%
Inhibition	=	67	%
Inhibition	=	7.5	%
Inhibition	=	21.2	%
Inhibition	=	2.9	%
Inhibition	=	55.1	%
Inhibition	=	10.5	%
Inhibition	=	18	%
Inhibition	=	30.1	%
Inhibition	=	30.1	%
Inhibition	=	43.9	%
Inhibition	=	37.2	%
Inhibition	=	12.7	%
Inhibition	<	10	%
Inhibition	=	16.6	%
Inhibition	=	7.2	%
Inhibition	=	20	%
Inhibition	=	89.3	%
Inhibition	=	8.1	%

71079-28-2 靶点实验数据