HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_3284_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	Target Accession(s)	Ligand	Target
IC50	0.04	40	O75460	BDBM110972	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.08	80	O75460	BDBM110974	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.1	100	O75460	BDBM110975	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.11	110	O75460	BDBM110976	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.17	170	O75460	BDBM110978	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.24	240	O75460	BDBM110980	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.24	240	O75460	BDBM110981	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.25	250	O75460	BDBM110982	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.27	270	O75460	BDBM110983	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.3	300	O75460	BDBM110985	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.35	350	O75460	BDBM110986	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.38	380	O75460	BDBM110987	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.38	380	O75460	BDBM110988	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.39	390	O75460	BDBM110989	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.4	400	O75460	BDBM110990	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.4	400	O75460	BDBM110991	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.4	400	O75460	BDBM110992	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.41	410	O75460	BDBM110993	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.44	440	O75460	BDBM110994	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.51	510	O75460	BDBM110995	Serine/threonine-protein kinase/endoribonuclease IRE1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_6134_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	Target Accession(s)	Ligand	Target
IC50	0.034	34	O75460	BDBM110972	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.079	79	O75460	BDBM110973	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.08	80	O75460	BDBM110974	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.1	100	O75460	BDBM110975	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.08	80	O75460	BDBM110975	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.11	110	O75460	BDBM110976	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.12	120	O75460	BDBM110977	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.17	170	O75460	BDBM110978	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.102	102	O75460	BDBM110979	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.102	102	O75460	BDBM110979	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.24	240	O75460	BDBM110980	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.24	240	O75460	BDBM110981	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.25	250	O75460	BDBM110982	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.27	270	O75460	BDBM110983	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.022	22	O75460	BDBM110983	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.28	280	O75460	BDBM110984	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.3	300	O75460	BDBM110985	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.772	772	O75460	BDBM110985	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.35	350	O75460	BDBM110986	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.38	380	O75460	BDBM110987	Serine/threonine-protein kinase/endoribonuclease IRE1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_7561_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	Target Accession(s)	Ligand	Target
IC50	0.034	34	O75460	BDBM110972	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.079	79	O75460	BDBM110973	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.08	80	O75460	BDBM110974	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.1	100	O75460	BDBM110975	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.08	80	O75460	BDBM110975	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.11	110	O75460	BDBM110976	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.17	170	O75460	BDBM110978	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.17	170	O75460	BDBM110979	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.102	102	O75460	BDBM110979	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.24	240	O75460	BDBM110980	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.24	240	O75460	BDBM110981	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.25	250	O75460	BDBM110982	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.27	270	O75460	BDBM110983	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.022	22	O75460	BDBM110983	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.28	280	O75460	BDBM110984	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.3	300	O75460	BDBM110985	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.772	772	O75460	BDBM110985	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.35	350	O75460	BDBM110986	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.38	380	O75460	BDBM110987	Serine/threonine-protein kinase/endoribonuclease IRE1
IC50	0.38	380	O75460	BDBM110988	Serine/threonine-protein kinase/endoribonuclease IRE1

708-76-9 靶点实验数据