HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：UDP-glucuronosyltransferase 2B17

External ID: CHEMBL867716

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2006
Volume: 49
Issue: 5
First Page: 1818
Last Page: 1827
DOI: 10.1021/jm051142c

Target ChEMBL ID: CHEMBL4978
ChEMBL Target Name: UDP-glucuronosyltransferase 2B17
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
	Imax	=	13.1	%
606	IC50	=	606000	nM	Outside typical range
	Imax	=	11.1	%
242	IC50	=	242000	nM	Outside typical range
	Imax	=	83.5	%
305	IC50	=	305000	nM	Outside typical range
	Imax	=	77.4	%
144	IC50	=	144000	nM	Outside typical range
	Imax	=	87.8	%
98	IC50	=	98000	nM
	Imax	=	74.8	%
365	IC50	=	365000	nM	Outside typical range
	Imax	=	72.6	%
325	IC50	=	325000	nM	Outside typical range
	Imax	=	75.3	%
682	IC50	=	682000	nM	Outside typical range
	Imax	=	60.1	%
608	IC50	=	608000	nM	Outside typical range
	Imax	=	61.7	%
517	IC50	=	517000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：UDP-glucuronosyltransferase 2B7

External ID: CHEMBL867715

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2006
Volume: 49
Issue: 5
First Page: 1818
Last Page: 1827
DOI: 10.1021/jm051142c

Target ChEMBL ID: CHEMBL4370
ChEMBL Target Name: UDP-glucuronosyltransferase 2B7
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment	Data Validity Comment
	Imax	=	19.8	%
532	IC50	=	532000	nM		Outside typical range
	Imax	=	17.7	%
337	IC50	=	337000	nM		Outside typical range
	Imax	=	61.9	%
651	IC50	=	651000	nM		Outside typical range
	Imax	=	62.5	%
158	IC50	=	158000	nM		Outside typical range
	Imax	=	85.7	%
166	IC50	=	166000	nM		Outside typical range
	Imax	=	68.7	%
225	IC50	=	225000	nM		Outside typical range
	Imax	=	83.5	%
182	IC50	=	182000	nM		Outside typical range
	Imax	=	85	%
	Imax				Not Determined
317	IC50	=	317000	nM		Outside typical range
	Imax	=	76	%
	Imax	=	86.4	%
275	IC50	=	275000	nM		Outside typical range

697-64-3 靶点实验数据