HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium thermophilum

External ID: CHEMBL910836

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL614752
ChEMBL Target Name: Bifidobacterium thermophilum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium breve

External ID: CHEMBL910837

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL5209644
ChEMBL Target Name: Bifidobacterium breve
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	1.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	15.6	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL3069285

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 6
First Page: 2553
Last Page: 2560
DOI: 10.1007/s00044-012-0253-1

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.12	ug.mL-1
MIC	=	8	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL910838

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL3069284

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 6
First Page: 2553
Last Page: 2560
DOI: 10.1007/s00044-012-0253-1

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	16	ug.mL-1
MIC	=	64	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：NCGC 靶标：

External ID: SNCA-p-activity-luciferase

Protocol: PROTOCOL TABLE
SEQUENCE No. (e.g., 1, 2, 3, etc.); PARAMETER (e.g., Cells, Incubation, Reagent, etc.); VALUE; DESCRIPTION

1; Cells; 4 uL; Dispense 1500 HEK-293-SNCA-luc cells/well into Greiner 1536-well white / solid bottom tissue culture treated plate. The plate was covered with metal lids with gas-exchange holes.
2; Incubate; 24 hours; Incubate at 37C, 5% CO2, 95% RH.
3; Compounds; 23 nL; Compounds and controls were transferred via a Kalypsys Pin Tool (Wako USA) equipped with a 1536-slotted pin array. The plate was covered with metal lids with gas-exchange holes.
4; Incubate; 24 hours; Incubate at 37C, 5% CO2, 95% RH.
5; Dispense; 1 uL; Dispense Gly-Phe-7-amino-4-trifluoromethylcoumarin (GF-AFC, prepared at 125 uM in PBS) was added. The plate was covered with metal lids with gas-exchange holes.
6; Incubate; 30 min; Incubate at 37C, 5% CO2.
7; Detector; Fluorescence; Measure fluorescence with ViewLux microplate reader (PerkinElmer) equipped with 405/10 excitation and 540/25 emission filters.
8; Dispense; 3 uL; Dispense ONE-Glo (PerkinElmer) lucifase detection reagent was added to each well. Plates were covered with metal lids with gas-exchange holes.
9; Incubate; 15 min; Incubate at room temperature.
10; Detector; Luminescence; Measure luminescence with ViewLux microplate reader (PerkinElmer) equipped with clear filters.

NOTES (numbers refer to sequence above)
1; HEK-293-SNCA-luc were cultured and suspended in phenol-red free DMEM (4.5 g/L glucose, 25 mM HEPES, cat #21063 (Thermo)).
3; Compounds were added to the assay plate in an 11-point intra plate dose response, 1:3 titration in DMSO with a final concentration range of xxx - yyy uM. Vehicle-only plates, with DMSO being pin-transferred to every well, were inserted at the beginning of screening runs to confirm expected assay performance. Activity was normalized to wells containing medium only (-100% activity, full inhibition) and SNCA-luc cells treated with DMSO vehicle control (0% activity), contained on the same plate as test samples.
10; Signals were analyzed, and dose-response curves were fit using the Hill equation. Compounds in curve classes -1.1, -1.2, -2.1, -2.2 in the SNCA-luc assay were considered active. Compounds were eliminated from further consideration if also active (curve class -1.1, -1.2, -1.3, -1.4, -2.1, -2.2, -2.3, -2.4) in the GF-AFC cytotoxicity assay.

Comment: Disclaimer:
Although all reasonable efforts have been made to ensure the accuracy and reliability of the data, caution should be exercised when interpreting the results as artifacts are possible from nonspecific effects such as assay signal interference. The curve fitting and activity calls presented here are based on the NCATS analysis methods.

Compound Ranking:
1. Compounds are first classified as having full titration curves, partial modulation, partial curve (weaker actives), single point activity (at highest concentration only), or inactive. For this assay, apparent inhibitors are ranked higher than compounds that showed apparent activation.
2. For all inactive compounds, with a ratio activity curve class of 4, PUBCHEM_ACTIVITY_SCORE is 0. For all active compounds, a score range was given for each curve class type given above. Active compounds have PUBCHEM_ACTIVITY_SCORE between 40 and 100. For a ratio activity curve class = -1.1, score = 80+abs((log_ac50+4.5)*inf_activity/20). For ratio.curve_class == -1.2 && abs(ratio.max_response) > 6*10, score = 60+abs((log_ac50+4.5)*inf_activity/20). For ratio.curve_class == -2.1 || ( ratio.curve_class==-2.2 && abs(ratio.max_response) > 6*10), score = 40+abs((log_ac50+4.5)*inf_activity/20). For ratio.curve_class == -1.2 || ratio.curve_class == -2.2, score = 20+abs((log_ac50+4.5)*inf_activity/20). Inconclusive compounds, with a donor curve class other than 4, have PUBCHEM_ACTIVITY_SCORE of 10. Inconclusive compounds have PUBCHEM_ACTIVITY_SCORE between 1 and 39.

Phenotype	Potency	Efficacy	Curve_Description	Fit_LogAC50	Fit_HillSlope	Fit_R2	Fit_InfiniteActivity	Fit_ZeroActivity	Fit_CurveClass	Excluded_Points	Max_Response	Activity at 0.079 uM	Activity at 1.068 uM	Activity at 11.39 uM	Activity at 57.25 uM	Compound QC
Inactive				-6.75	4.9549	0.9727	0.0901	17.5	4	0 0 0 1	8.9408	15.9527	-1.5916	1.4969	8.9408	QC'd by Sytravon
Inactive				-5.3	4.095	0.9996	5.5	-7.7823	4	0 0 0 1	-11.1081	-7.5736	-7.7353	5.034	-11.1081	QC'd by Sytravon
Inactive				-5.15	4.9549	0.907	-15.9207	9.5	4	0 0 0 1	17.8725	5.2874	13.9021	-13.6839	17.8725	QC'd by Sytravon
Activator	35.4813	46.4095	Single point of activity	-4.45	2.5884	1	45.9404	-0.4691	3	1 0 0 0	35.593	40.1678	-0.3909	1.933	35.593	QC'd by Sytravon
Activator	39.8107	72.2646	Single point of activity	-4.4	4.9549	0.9515	68.1912	-4.0733	3	0 0 0 0	58.0117	5.8738	-9.2278	-8.5224	58.0117	QC'd by Sytravon
Activator	14.1254	45.3319	Partial curve; partial efficacy; poor fit	-4.85	2.4064	0.9982	40.7728	-4.5591	2.4	1 0 0 0	40.0933	-24.9557	-3.8845	11.5254	40.0933	QC'd by Sytravon
Inactive				-5.75	4.9549	0.9291	-20.6086	33.1545	4	1 0 0 0	-12.8464	45.4569	28.2161	-28.42	-12.8464	QC'd by Sytravon
Inactive				-4.35	4.9549	0.855	-24.2184	-0.5	4	0 0 0 0	-18.932	-3.6477	-2.409	4.988	-18.932	QC'd by Sytravon
Inactive				-4.7	3.6272	0.8625	15	-8.5523	4	0 0 0 0	14.477	-2.951	-13.7936	-5.9646	14.477	QC'd by Sytravon
Inactive				-6.7	4.9549	0.6637	3	-16.864	4	0 0 0 0	8.8169	-15.72	6.3794	-6.3599	8.8169	QC'd by Sytravon
Inactive				-4.75	2.4064	0.9999	21.5	-2.4101	4	1 0 0 0	20.2184	33.3778	-2.4251	3.5771	20.2184	QC'd by Sytravon
Inactive				-4.4	4.9549	0.8117	2.5	-8.345	4	0 0 0 0	1.096	-8.966	-5.5054	-11.1209	1.096	QC'd by Sytravon
Activator	39.8107	38.7945	Single point of activity	-4.4	4.9549	0.6241	41.7557	2.9612	3	0 0 0 0	36.2039	21.355	-6.3904	-4.5325	36.2039	QC'd by Sytravon
Inactive				-6.05	4.095	0.9994	-6.0518	20	4	0 0 0 1	20.5156	19.7377	1.4122	-6.2932	20.5156	QC'd by Sytravon
Inactive				-5.2	4.095	1	10.5	-10.1683	4	1 0 0 1	-15.9884	36.1362	-10.1402	8.7939	-15.9884	QC'd by Sytravon
Inactive				-6.5	1.3905	0.9999	-24.241	0.2745	4	0 0 0 1	-5.5981	-4.3546	-20.7587	-23.9509	-5.5981	QC'd by Sytravon
Inactive				-6.8	4.9549	0.711	-2.4459	21	4	0 0 0 0	-3.3453	17.3219	-9.9549	5.5495	-3.3453	QC'd by Sytravon
Activator	39.8107	47.809	Partial curve; partial efficacy; poor fit	-4.4	4.9549	0.5212	50.2399	2.4309	2.4	0 0 0 0	43.4722	30.2363	-10.9855	-11.5143	43.4722	QC'd by Sytravon
Activator	22.3872	75.5081	Partial curve; high efficacy; poor fit	-4.65	1.9673	0.9829	96.5324	21.0243	2.3	0 0 0 0	86.4985	26.0932	16.3365	36.2613	86.4985	QC'd by Sytravon
Inactive				-6.8	4.9549	0.7429	-1	-13.0738	4	0 0 0 0	1.8063	-11.3115	0.8702	-5.1757	1.8063	QC'd by Sytravon

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium bifidum

External ID: CHEMBL910839

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL4523075
ChEMBL Target Name: Bifidobacterium bifidum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	1.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Enterococcus faecalis

External ID: CHEMBL3069287

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 6
First Page: 2553
Last Page: 2560
DOI: 10.1007/s00044-012-0253-1

Target ChEMBL ID: CHEMBL362
ChEMBL Target Name: Enterococcus faecalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	1	ug.mL-1
MIC	=	2	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910832

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Enterococcus faecalis

External ID: CHEMBL3069286

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 6
First Page: 2553
Last Page: 2560
DOI: 10.1007/s00044-012-0253-1

Target ChEMBL ID: CHEMBL362
ChEMBL Target Name: Enterococcus faecalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	2	ug.mL-1
MIC	=	4	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910833

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	3.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	62.5	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL3069289

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 6
First Page: 2553
Last Page: 2560
DOI: 10.1007/s00044-012-0253-1

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.5	ug.mL-1
MIC	=	2	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：824 靶标：

External ID: CYP273

Protocol: Tox21 Assay Protocol Summary:

Two ul of enzyme-substrate mix was dispensed into medium binding white/solid 1536-well plates (Greiner Bio-One North America Inc., Monroe, NC) using a BioRaptr Flying Reagent Dispenser (FRD, Beckman Coulter, Brea, CA). Compounds dissolved in DMSO and positive control (furafyllline) were transferred to the assay plates at 23 nl using a Pintool station (Wako, San Diego, CA). The assay plates were incubated at room temperature for 10 min. Then 2 ul of NADPH regeneration solution was added to each well of the assay plates using an FRD and incubated at room temperature for 1 h. The reaction was stopped by adding 4 ul of detection reagent using an FRD and after 20 min incubation at room temperature the luminescence signal was measured using a ViewLux plate reader (Perkin Elmer, Shelton, CT). Data were expressed as relative luminescence units.

Comment: Disclaimer:

Although all reasonable efforts have been made to ensure the accuracy and reliability of the data, caution should be exercised when interpreting the results as artifacts are possible from nonspecific effects such as assay signal interference. The curve fitting and activity calls presented here are based on the NCATS analysis methods. Alternative analysis methods and interpretations of the data are available at EPA (http://actor.epa.gov) and NTP (http://tools.niehs.nih.gov/cebs3/ui/).

Compound Ranking:

1. Compounds are first classified as having full titration curves, partial modulation, partial curve (weaker actives), single point activity (at highest concentration only), or inactive. See data field "Curve Description". For this assay, apparent inhibitors are ranked higher than compounds that showed apparent activation.
2. For all inactive compounds, PUBCHEM_ACTIVITY_SCORE is 0. For all active compounds, a score range was given for each curve class type given above. Active compounds have PUBCHEM_ACTIVITY_SCORE between 40 and 100. Inconclusive compounds have PUBCHEM_ACTIVITY_SCORE between 1 and 39. Fit_LogAC50 was used for determining relative score and was scaled to each curve class' score range.

Phenotype-Replicate_1	Potency-Replicate_1	Efficacy-Replicate_1	Activity_Score-Replicate_1	Curve_Description-Replicate_1	Fit_LogAC50-Replicate_1	Fit_HillSlope-Replicate_1	Fit_R2-Replicate_1	Fit_InfiniteActivity-Replicate_1	Fit_ZeroActivity-Replicate_1	Fit_CurveClass-Replicate_1	Excluded_Points-Replicate_1	Max_Response-Replicate_1	Activity at 0.0007781017 uM-Replicate_1	Activity at 0.00212 uM-Replicate_1	Activity at 0.00657 uM-Replicate_1	Activity at 0.017 uM-Replicate_1	Activity at 0.038 uM-Replicate_1	Activity at 0.085 uM-Replicate_1	Activity at 0.191 uM-Replicate_1	Activity at 0.435 uM-Replicate_1	Activity at 1.330 uM-Replicate_1	Activity at 4.074 uM-Replicate_1	Activity at 10.46 uM-Replicate_1	Activity at 23.64 uM-Replicate_1	Activity at 52.95 uM-Replicate_1	Activity at 115.2 uM-Replicate_1	Compound QC-Replicate_1	Phenotype-Replicate_2	Potency-Replicate_2	Efficacy-Replicate_2	Activity_Score-Replicate_2	Curve_Description-Replicate_2	Fit_LogAC50-Replicate_2	Fit_HillSlope-Replicate_2	Fit_R2-Replicate_2
Inactive			0					0	0	4		-3.5643		-2.3504	-2.9312	-2.3657	-2.8224	-2.6018	0.0394	2.8539	-0.9099	-0.8614	-3.0049	-2.5808	-0.7	-3.5643	QC'd by SIGMA	Inactive			0
Inactive			0					0	0	4		-4.9449		-1.1401	-4.8828	1.7278	1.7167	-2.1117	-5.6964	0.3933	0.8939	0.1314	-2.7335	3.195	-4.9521	-4.9449	QC'd by SIGMA	Inactive			0
Inactive			0					0	0	4		2.7107		-2.1884	1.3985	1.4582	0.7693	-2.4787	1.52	2.8986	0.9702	-0.0253	2.1293	2.7766	1.539	2.7107	QC'd by Enamine	Inactive			0
Inactive			0					0	0	4		-2.1522		-2.3143	-3.894	-2.3698	3.0635	-2.9724	-0.698	1.807	-0.3874	-2.2387	0.0851	-4.1965	3.0171	-2.1522	QC'd by SIGMA	Inactive			0
Inactive			0		-4.3489	2.2526	0.8543	-15.2749	-1.5	4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-14.3957		-1.8486	-1.8251	-1.3415	-0.2999	-5.8043	-1.4625	0.152	0.0394	-2.6869	-2.4228	-2.2664	-9.6519	-14.3957	QC'd by SIGMA	Inactive			0		-4.0989	2.1876	0.881
Inactive			0		-4.3989	1.3443	0.8661	-18.2112	-1	4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-16.0093		-2.3466	0.8145	0.3878	-0.5249	-2.2045	-0.0596	-0.3675	-2.1137	-2.5302	-0.6582	-8.8446	-8.7305	-16.0093	QC'd by Acros	Inactive			0		-4.1989	1.6266	0.9372
Inactive			0		-4.3713	1.331	0.7782	-33.4439	-3.503	4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-29.5366	-4.0189	-0.7745	-2.4487	-0.7353	-13.4714	-1.9963	-2.0808	-1.5803	-2.9931	-5.0804	-13.0346	-7.2628	-16.8143	-29.5366	QC'd by LightBiologicals	Inactive			0		-4.3713	1.2221	0.9463
Inactive			0		-4.1489	1.6266	0.9461	-28.1716	-1	4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-20.143		-1.7608	-0.2388	0.2248	0.5264	-2.4986	-0.1313	-2.2365	-0.2423	-3.4362	-3.0971	-3.2181	-11.2156	-20.143	QC'd by Enamine	Inhibitor	79.6407	31.4916	10	Partial curve; partial efficacy; poor fit	-4.0989	2.5884	0.988
Inhibitor	79.6407	37.8784	10	Partial curve; partial efficacy; poor fit	-4.0989	2.3332	0.6037	-41.3784	-3.5	-2.4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-31.1486		0.0477	-0.2424	-0.1109	-17.1482	-2.6043	0.0987	1.3021	-8.8121	-0.6811	-2.6079	-6.0005	-11.8578	-31.1486	QC'd by LightBiologicals	Inhibitor	70.9799	33.8113	10	Partial curve; partial efficacy; poor fit	-4.1489	1.4787	0.9532
Inactive			0		-4.1489	1.331	0.6595	-35.6335	-1	4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-26.3612		1.8269	-1.2651	2.0528	-1.3342	-1.1508	-1.3078	-0.329	-8.1235	0.9213	-0.3901	-8.3475	-13.4823	-26.3612	QC'd by LightBiologicals	Inhibitor	63.2609	40.7162	21	Partial curve; partial efficacy	-4.1989	1.5579	0.9889
Inhibitor	31.7055	100.2192	40	Partial curve; high efficacy	-4.4989	1.4163	0.9793	-102.2947	-2.0755	-2.1	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-88.7975		1.5993	1.9578	-0.4182	-5.9156	-12.3257	-6.8125	0.6301	-0.9357	-7.8675	-21.9718	-39.1747	-68.2733	-88.7975	QC'd by SIGMA	Inhibitor	28.2576	108.4027	40	Partial curve; high efficacy	-4.5489	1.2475	0.9984
Inactive			0		-4.4489	1.5386	0.9285	-23.7863	1	4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-21.4885		2.5819	2.144	-0.9228	1.5778	0.3813	-0.7273	-0.0178	0.4803	2.4385	-0.728	-9.9293	-11.8247	-21.4885	QC'd by SIGMA	Inactive			0		-4.3989	1.6259	0.9598
Inhibitor	9.3337	39.8967	21	Complete curve; partial efficacy	-5.0299	2.0437	0.9899	-39.8967	0	-1.2	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-36.3129	-0.2423	-0.4463	-0.2999	0.6478	0.3636	1.006	-0.4987	1.2825	-1.1546	-7.8589	-17.895	-35.8398	-36.3129		QC'd by LightBiologicals	Inhibitor	11.7504	56.3884	21	Partial curve; partial efficacy	-4.9299	1.111	0.9845
Inhibitor	31.7055	101.4573	40	Partial curve; high efficacy	-4.4989	1.111	0.9982	-102.7597	-1.3024	-2.1	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-82.349		-1.7206	-3.1014	-1.0307	-0.462	-0.0614	-0.5481	-3.1286	-4.6801	-13.1432	-23.5612	-42.1146	-67.192	-82.349	QC'd by SIGMA	Inhibitor	25.1846	89.5091	40	Partial curve; high efficacy	-4.5989	1.3723	0.9943
Inactive			0		-4.3989	1.3723	0.9408	-30.7143	-1.5	4	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-27.2619		-3.9038	-4.2597	0.9522	0.2767	-0.086	-3.7725	-0.0863	-0.3476	-4.4856	-5.6587	-11.4378	-17.5999	-27.2619	QC'd by Enamine	Inactive			0		-4.3989	1.3723	0.9104
Inhibitor	0.02	91.5374	95	Complete curve; high efficacy	-7.6989	1.21	0.9985	-95.5053	-3.9679	-1.1	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-96.9758		-10.1145	-26.2532	-42.3865	-67.4835	-79.9456	-90.8539	-91.593	-94.2489	-95.4721	-96.0956	-96.1267	-97.0582	-96.9758	QC'd by SIGMA	Inhibitor	0.1416	94.8402	91	Complete curve; high efficacy	-6.8489	1.21	0.9987
Inhibitor	70.9799	57.4014	21	Partial curve; partial efficacy	-4.1489	1.4641	0.9678	-60.4859	-3.0846	-2.2	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-45.8227		-1.5241	-1.1304	-2.119	-3.4583	-2.7138	-4.9163	-1.3699	-5.0741	-7.7268	-8.2608	-10.3758	-24.1789	-45.8227	QC'd by TCI	Inhibitor	63.2609	59.3706	21	Partial curve; partial efficacy	-4.1989	1.8265	0.9826
Inhibitor	31.7055	88.4583	40	Partial curve; high efficacy	-4.4989	1.2475	0.9907	-90.0614	-1.6031	-2.1	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-73.0646		-2.1792	-0.7242	-0.9217	-2.0267	-1.1711	-1.4022	-1.5555	-4.0648	-12.1704	-19.1709	-32.2561	-64.0802	-73.0646	QC'd by SIGMA	Inhibitor	31.7055	86.8385	40	Partial curve; high efficacy	-4.4989	1.111	0.9934
Inhibitor	7.098	99.9448	83	Complete curve; high efficacy	-5.1489	1.3443	0.9949	-102.6257	-2.681	-1.1	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-98.8687		-2.2636	-1.9377	-0.2674	-0.3864	-3.2139	-8.5636	-4.0834	-14.5383	-36.543	-60.2337	-91.3595	-96.848	-98.8687	QC'd by TCI	Inhibitor	5.6381	99.0727	84	Complete curve; high efficacy	-5.2489	1.6266	0.998
Inhibitor	14.1623	99.522	42	Partial curve; high efficacy	-4.8489	0.7	0.9894	-100.6417	-1.1197	-2.1	0 0 0 0 0 0 0 0 0 0 0 0 0 0 0	-88.2822		-1.4919	-2.9847	-0.2649	-1.6478	-3.8502	-2.8959	-7.6423	-18.6375	-36.1235	-44.1844	-53.91	-71.7844	-88.2822	QC'd by SIGMA	Inhibitor	17.8293	95.7742	81	Complete curve; high efficacy	-4.7489	1.21	0.9995

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910834

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL3069288

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 6
First Page: 2553
Last Page: 2560
DOI: 10.1007/s00044-012-0253-1

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	2	ug.mL-1
MIC	=	32	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL910835

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910844

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910845

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	31.2	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910846

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	62.5	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL910847

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium bifidum

External ID: CHEMBL910840

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL4523075
ChEMBL Target Name: Bifidobacterium bifidum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium breve

External ID: CHEMBL910841

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL5209644
ChEMBL Target Name: Bifidobacterium breve
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium breve

External ID: CHEMBL910842

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL5209644
ChEMBL Target Name: Bifidobacterium breve
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	1.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL910843

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium bifidum

External ID: CHEMBL910852

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL4523075
ChEMBL Target Name: Bifidobacterium bifidum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	500	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium breve

External ID: CHEMBL910853

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL5209644
ChEMBL Target Name: Bifidobacterium breve
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bacillus cereus

External ID: CHEMBL3070139

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 5
First Page: 2531
Last Page: 2537
DOI: 10.1007/s00044-012-0248-y

Target ChEMBL ID: CHEMBL613070
ChEMBL Target Name: Bacillus cereus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC	=	62.5	ug.mL-1
MBC				Not Determined
MIC	=	31.25	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium breve

External ID: CHEMBL910854

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL5209644
ChEMBL Target Name: Bifidobacterium breve
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Micrococcus luteus

External ID: CHEMBL3070138

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 5
First Page: 2531
Last Page: 2537
DOI: 10.1007/s00044-012-0248-y

Target ChEMBL ID: CHEMBL614421
ChEMBL Target Name: Micrococcus luteus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC	=	0.98	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL910855

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus epidermidis

External ID: CHEMBL3070141

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 5
First Page: 2531
Last Page: 2537
DOI: 10.1007/s00044-012-0248-y

Target ChEMBL ID: CHEMBL353
ChEMBL Target Name: Staphylococcus epidermidis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC	=	0.24	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium thermophilum

External ID: CHEMBL910848

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL614752
ChEMBL Target Name: Bifidobacterium thermophilum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bacillus subtilis

External ID: CHEMBL3070140

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 5
First Page: 2531
Last Page: 2537
DOI: 10.1007/s00044-012-0248-y

Target ChEMBL ID: CHEMBL359
ChEMBL Target Name: Bacillus subtilis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC	=	15.63	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL910849

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium bifidum

External ID: CHEMBL910850

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL4523075
ChEMBL Target Name: Bifidobacterium bifidum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL3070142

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 5
First Page: 2531
Last Page: 2537
DOI: 10.1007/s00044-012-0248-y

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MBC	=	3.91	ug ml-1
MIC	=	0.98	ug.mL-1
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium bifidum

External ID: CHEMBL910851

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL4523075
ChEMBL Target Name: Bifidobacterium bifidum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	1.9	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL912627

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL3070552

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2013
Volume: 22
Issue: 5
First Page: 2531
Last Page: 2537
DOI: 10.1007/s00044-012-0248-y

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC				Not Determined
MBC				Not Determined
MIC	=	0.49	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium thermophilum

External ID: CHEMBL912628

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL614752
ChEMBL Target Name: Bifidobacterium thermophilum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL912629

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium bifidum

External ID: CHEMBL912630

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL4523075
ChEMBL Target Name: Bifidobacterium bifidum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910856

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	62.5	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL910857

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL912625

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL912626

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	62.5	ug.mL-1
MIC	=	125	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL912635

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	7.8	ug.mL-1
MIC	=	3.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	500	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Salmonella enterica subsp. enterica serovar Typhimurium

External ID: CHEMBL1037014

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2010
Volume: 45
Issue: 2
First Page: 510
Last Page: 518
DOI: 10.1016/j.ejmech.2009.10.037

Target ChEMBL ID: CHEMBL351
ChEMBL Target Name: Salmonella typhimurium
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
IZ	Not Active
IZ	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifidobacterium longum

External ID: CHEMBL912636

Protocol: N/A

Comment: Journal: Antimicrob Agents Chemother
Year: 2007
Volume: 51
Issue: 1
First Page: 169
Last Page: 174
DOI: 10.1128/aac.00261-06

Target ChEMBL ID: CHEMBL613911
ChEMBL Target Name: Bifidobacterium longum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.98	ug.mL-1
MIC	=	0.98	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	>	500	ug.mL-1
MIC	=	31.2	ug.mL-1
MIC	=	1.9	ug.mL-1
MIC	=	500	ug.mL-1
MIC	=	15.6	ug.mL-1
MIC	=	250	ug.mL-1
MIC	=	125	ug.mL-1
MIC	=	250	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Listeria monocytogenes

External ID: CHEMBL1037015

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2010
Volume: 45
Issue: 2
First Page: 510
Last Page: 518
DOI: 10.1016/j.ejmech.2009.10.037

Target ChEMBL ID: CHEMBL614974
ChEMBL Target Name: Listeria monocytogenes
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
IZ				Not Active
IZ				Not Active

69-53-4 靶点实验数据