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68352-27-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium kansasii
External ID: CHEMBL2446813
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 21
First Page: 6531
Last Page: 6541
DOI: 10.1016/j.bmc.2013.08.030

Target ChEMBL ID: CHEMBL614984
ChEMBL Target Name: Mycobacterium kansasii
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
860MIC=860000nM
57.7MIC=57700nM
23.3MIC=23300nM
748MIC>748000nM
51.9MIC=51900nM
773MIC>773000nM
748MIC>748000nM
830MIC>830000nM
873MIC>873000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycolicibacterium smegmatis
External ID: CHEMBL2446812
Protocol: N/A
Comment: Journal: Bioorg Med Chem
Year: 2013
Volume: 21
Issue: 21
First Page: 6531
Last Page: 6541
DOI: 10.1016/j.bmc.2013.08.030

Target ChEMBL ID: CHEMBL613088
ChEMBL Target Name: Mycolicibacterium smegmatis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
860MIC=860000nM
923MIC=923000nM
46.7MIC=46700nM
748MIC>748000nM
830MIC>830000nM
773MIC>773000nM
748MIC>748000nM
830MIC>830000nM
873MIC>873000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2446811
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 21
First Page: 6531
Last Page: 6541
DOI: 10.1016/j.bmc.2013.08.030
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
29.4IC50=29400nM
28.7IC50=28700nM
9.6IC50=9600nM
61.9IC50=61900nM
24IC50=24000nM
126.1IC50=126100nMOutside typical range
8.2IC50=8200nM
19.9IC50=19900nM
199.6IC50=199600nMOutside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Rodentolepis nana
External ID: CHEMBL3257479
Protocol: N/A
Comment: Journal: J Med Chem
Year: 1978
Volume: 21
Issue: 11
First Page: 1178
Last Page: 1181
DOI: 10.1021/jm00209a020

Target ChEMBL ID: CHEMBL612450
ChEMBL Target Name: Rodentolepis nana
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
ActivityNot Active
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2447061
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 21
First Page: 6531
Last Page: 6541
DOI: 10.1016/j.bmc.2013.08.030
Standard TypeStandard RelationStandard Value
log K=1.23
log K=0.8764
log K=1.161
log K=1.188
log K=1.118
log K=0.5298
log K=1.285
log K=1.425
log K=1.472
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium marinum
External ID: CHEMBL2447060
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 21
First Page: 6531
Last Page: 6541
DOI: 10.1016/j.bmc.2013.08.030

Target ChEMBL ID: CHEMBL614987
ChEMBL Target Name: Mycobacterium marinum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
107MIC=107000nM
115MIC=115000nM
46.7MIC=46700nM
748MIC>748000nM
104MIC=104000nM
96.6MIC=96600nM
748MIC>748000nM
830MIC>830000nM
873MIC>873000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2446807
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 21
First Page: 6531
Last Page: 6541
DOI: 10.1016/j.bmc.2013.08.030
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=10%
Inhibition=10%
Inhibition=10%
Inhibition=10%
Inhibition=10%
Inhibition=10%
Inhibition=10%
Inhibition=10%
Inhibition=10%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2446806
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 21
First Page: 6531
Last Page: 6541
DOI: 10.1016/j.bmc.2013.08.030
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=95%
Inhibition=95%
Inhibition=95%
Inhibition=95%
Inhibition=95%
Inhibition=95%
Inhibition=95%
Inhibition=95%
Inhibition=95%