HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_3505_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	Ki	Target Accession(s)	Ligand	Target
Ki	0.0072	7.2	P35218	BDBM35726	Carbonic anhydrase 5A, mitochondrial
Ki	0.007	7	Q9Y2D0	BDBM35726	Carbonic anhydrase 5B, mitochondrial
Ki	0.161	161	P00915	BDBM35727	Carbonic anhydrase 1
Ki	0.39	390	P00918	BDBM35727	Carbonic anhydrase 2
Ki	0.0091	9.1	P35218	BDBM35730	Carbonic anhydrase 5A, mitochondrial
Ki	0.0072	7.2	Q9Y2D0	BDBM35730	Carbonic anhydrase 5B, mitochondrial
Ki	0.068	68	P00915	BDBM35731	Carbonic anhydrase 1
Ki	0.053	53	P00918	BDBM35731	Carbonic anhydrase 2
Ki	0.0102	10.2	P35218	BDBM35731	Carbonic anhydrase 5A, mitochondrial
Ki	0.008	8	Q9Y2D0	BDBM35731	Carbonic anhydrase 5B, mitochondrial
Ki	0.072	72	P00915	BDBM35732	Carbonic anhydrase 1
Ki	0.051	51	P00918	BDBM35732	Carbonic anhydrase 2
Ki	0.0067	6.7	P35218	BDBM35733	Carbonic anhydrase 5A, mitochondrial
Ki	0.0079	7.9	Q9Y2D0	BDBM35733	Carbonic anhydrase 5B, mitochondrial
Ki	0.075	75	P00915	BDBM35734	Carbonic anhydrase 1
Ki	0.054	54	P00918	BDBM35734	Carbonic anhydrase 2
Ki	0.0086	8.6	P35218	BDBM35734	Carbonic anhydrase 5A, mitochondrial
Ki	0.0083	8.3	Q9Y2D0	BDBM35734	Carbonic anhydrase 5B, mitochondrial
Ki	0.06	60	P00915	BDBM35735	Carbonic anhydrase 1
Ki	0.067	67	P00918	BDBM35735	Carbonic anhydrase 2

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1046602

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 14
First Page: 4894
Last Page: 4899
DOI: 10.1016/j.bmc.2009.06.006

Standard Type	Standard Relation	Standard Value
Ratio Ki	=	0.05
Ratio Ki	=	0.05
Ratio Ki	=	5.8
Ratio Ki	=	5.8
Ratio Ki	=	5.8
Ratio Ki	=	13.5
Ratio Ki	=	5.8
Ratio Ki	=	5.8
Ratio Ki	=	0.05

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1788075

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2009
Volume: 19
Issue: 12
First Page: 3170
Last Page: 3173
DOI: 10.1016/j.bmcl.2009.04.123

Standard Type	Standard Relation	Standard Value
Ratio Ki	=	10
Ratio Ki	=	4.8
Ratio Ki	=	0.29
Ratio Ki	=	8.06
Ratio Ki	=	7.32
Ratio Ki	=	6.97
Ratio Ki	=	22.76
Ratio Ki	=	7.94
Ratio Ki	=	8.4
Ratio Ki	=	11.11

68252-75-5 靶点实验数据