HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sodium- and chloride-dependent GABA transporter 1

External ID: CHEMBL4342201

Protocol: N/A

Comment: Journal: Bioorg Med Chem
Year: 2019
Volume: 27
Issue: 13
First Page: 2753
Last Page: 2763
DOI: 10.1016/j.bmc.2019.05.001

Target ChEMBL ID: CHEMBL5445
ChEMBL Target Name: GABA transporter 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	57	%
Activity	=	48	%
Activity	=	79	%
Activity	=	79	%
Activity	=	79	%
Activity	=	87	%
Activity	=	65	%
Activity	=	81	%
Activity	=	59	%
Activity	=	59	%
Activity	=	85	%
Activity	=	79	%
Activity	=	59	%
Activity	=	20	%
Activity	=	59	%
Activity	=	36	%
Activity	=	65	%
Activity	=	65	%
Activity	=	79	%
Activity	=	55	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycobacterium tuberculosis

External ID: CHEMBL1936447

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2012
Volume: 22
Issue: 1
First Page: 649
Last Page: 652
DOI: 10.1016/j.bmcl.2011.10.064

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.4	ug.mL-1
MIC	=	221.87	ug.mL-1
MIC	=	232.8	ug.mL-1
MIC	=	287.5	ug.mL-1
MIC	=	132.81	ug.mL-1
MIC	=	123.44	ug.mL-1
MIC	=	117.19	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sodium- and chloride-dependent GABA transporter 1

External ID: CHEMBL4401740

Protocol: N/A

Comment: Journal: Bioorg Med Chem
Year: 2019
Volume: 27
Issue: 7
First Page: 1232
Last Page: 1245
DOI: 10.1016/j.bmc.2019.02.015

Target ChEMBL ID: CHEMBL5445
ChEMBL Target Name: GABA transporter 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	94	%
Activity	=	85	%
Activity	=	89	%
Activity	=	89	%
Activity	=	90	%
Activity	=	90	%
Activity	=	90	%
Activity	=	90	%
Activity	=	90	%
Activity	=	90	%
Activity	=	89	%
Activity	=	92	%
Activity	=	92	%
Activity	=	89	%
Activity	=	92	%
Activity	=	94	%
Activity	=	87	%
Activity	=	90	%
Activity	=	93	%
Activity	=	92	%

67-36-7 靶点实验数据