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66947-62-4 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HeLa
External ID: CHEMBL4817809
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2021
Volume: 41
First Page: 127976
Last Page: 127976
DOI: 10.1016/j.bmcl.2021.127976

Target ChEMBL ID: CHEMBL399
ChEMBL Target Name: HeLa
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
71.26IC50=71260nM
23.79IC50=23790nM
7.06IC50=7060nM
21.68IC50=21680nM
13.85IC50=13850nM
12.53IC50=12530nM
37.86IC50=37860nM
22.69IC50=22690nM
8.86IC50=8860nM
5.21IC50=5210nM
35.32IC50=35320nM
12.24IC50=12240nM
27.17IC50=27170nM
19.15IC50=19150nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL4817810
Protocol: N/A
Comment: Journal: Bioorg Med Chem Lett
Year: 2021
Volume: 41
First Page: 127976
Last Page: 127976
DOI: 10.1016/j.bmcl.2021.127976
Standard TypeStandard RelationStandard ValueStandard Units
Activity=-0.346mV
Activity=-0.204mV
Activity=-0.431mV
Activity=-0.304mV
Activity=-0.208mV
Activity=-0.192mV
Activity=-0.165mV
Activity=-0.16mV
Activity=-0.196mV
Activity=-0.32mV
Activity=-0.197mV
Activity=-0.416mV
Activity=-0.18mV
Activity=-0.165mV
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:KB
External ID: CHEMBL4817808
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2021
Volume: 41
First Page: 127976
Last Page: 127976
DOI: 10.1016/j.bmcl.2021.127976

Target ChEMBL ID: CHEMBL398
ChEMBL Target Name: KB
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
105.48IC50=105480nMOutside typical range
16.91IC50=16910nM
13.26IC50=13260nM
23.81IC50=23810nM
8.48IC50=8480nM
13.42IC50=13420nM
64.2IC50=64200nM
33.9IC50=33900nM
18.29IC50=18290nM
6.23IC50=6230nM
41.54IC50=41540nM
18.76IC50=18760nM
10.18IC50=10180nM
12.08IC50=12080nM