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6587-21-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Giardia intestinalis
External ID: CHEMBL3227496
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: MedChemComm
Year: 2011
Volume: 2
Issue: 1
First Page: 44
Last Page: 49
DOI: 10.1039/C0MD00159G

Target ChEMBL ID: CHEMBL612652
ChEMBL Target Name: Giardia intestinalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.12IC50=120nM
0.25119IC50=251.19nM
0.25119IC50=251.19nM
0.05623IC50=56.23nM
0.056IC50=56nM
0.56234IC50=562.34nM
0.56IC50=560nM
0.23988IC50=239.88nM
0.02291IC50=22.91nM
0.023IC50=23nM
1.09648IC50=1096.48nM
0.03802IC50=38.02nM
0.10471IC50=104.71nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Giardia intestinalis
External ID: CHEMBL1273702
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 21
First Page: 7380
Last Page: 7391
DOI: 10.1016/j.bmc.2010.09.019

Target ChEMBL ID: CHEMBL612652
ChEMBL Target Name: Giardia intestinalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.23988IC50=239.88nM
0.02291IC50=22.91nM
1.09648IC50=1096.48nM
10.4713IC50=10471.29nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Trichomonas vaginalis
External ID: CHEMBL3227495
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: MedChemComm
Year: 2011
Volume: 2
Issue: 1
First Page: 44
Last Page: 49
DOI: 10.1039/C0MD00159G

Target ChEMBL ID: CHEMBL612884
ChEMBL Target Name: Trichomonas vaginalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.22IC50=220nM
0.19055IC50=190.55nM
0.19055IC50=190.55nM
0.001995IC50=1.995nM
0.002IC50=2nM
0.302IC50=302nM
0.3IC50=300nM
0.57544IC50=575.44nM
10IC50=10000nM
10.1IC50=10100nM
29.5121IC50=29512.09nM
0.27IC50=270nM
0.69183IC50=691.83nM
0.69183IC50=691.83nM
0.14791IC50=147.91nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Entamoeba histolytica
External ID: CHEMBL4191479
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2017
Volume: 137
First Page: 211
Last Page: 220
DOI: 10.1016/j.ejmech.2017.05.058

Target ChEMBL ID: CHEMBL612853
ChEMBL Target Name: Entamoeba histolytica
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.302IC50=302nM
0.20893IC50=208.93nM
1.54882IC50=1548.82nM
0.22909IC50=229.09nM
13.8038IC50=13803.84nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Giardia intestinalis
External ID: CHEMBL4191478
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2017
Volume: 137
First Page: 211
Last Page: 220
DOI: 10.1016/j.ejmech.2017.05.058

Target ChEMBL ID: CHEMBL612652
ChEMBL Target Name: Giardia intestinalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.05623IC50=56.23nM
0.56234IC50=562.34nM
0.23988IC50=239.88nM
0.02291IC50=22.91nM
0.02089IC50=20.89nM
0.14125IC50=141.25nM
0.02884IC50=28.84nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Entamoeba histolytica
External ID: CHEMBL915565
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2007
Volume: 15
Issue: 2
First Page: 1117
Last Page: 1126
DOI: 10.1016/j.bmc.2006.10.019

Target ChEMBL ID: CHEMBL612853
ChEMBL Target Name: Entamoeba histolytica
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.02188IC50=21.88nM
0.03981IC50=39.81nM
0.04571IC50=45.71nM
0.02512IC50=25.12nM
0.0955IC50=95.5nM
0.35481IC50=354.81nM
0.005012IC50=5.012nM
0.04169IC50=41.69nM
0.13183IC50=131.83nM
0.05495IC50=54.95nM
0.007079IC50=7.079nM
0.11482IC50=114.82nM
0.05888IC50=58.88nM
0.0389IC50=38.9nM
0.19055IC50=190.55nM
0.38905IC50=389.05nM
0.08318IC50=83.18nM
1.31826IC50=1318.26nM
0.42658IC50=426.58nM
0.05012IC50=50.12nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Trichomonas vaginalis
External ID: CHEMBL4191480
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2017
Volume: 137
First Page: 211
Last Page: 220
DOI: 10.1016/j.ejmech.2017.05.058

Target ChEMBL ID: CHEMBL612884
ChEMBL Target Name: Trichomonas vaginalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.001995IC50=1.995nM
0.302IC50=302nM
0.57544IC50=575.44nM
10IC50=10000nM
0.07244IC50=72.44nM
0.26915IC50=269.15nM
0.30903IC50=309.03nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Trichomonas vaginalis
External ID: CHEMBL1273701
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 21
First Page: 7380
Last Page: 7391
DOI: 10.1016/j.bmc.2010.09.019

Target ChEMBL ID: CHEMBL612884
ChEMBL Target Name: Trichomonas vaginalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.57544IC50=575.44nM
10IC50=10000nM
29.5121IC50=29512.09nM
0.19953IC50=199.53nM