HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cannabinoid receptor 1

External ID: CHEMBL658112

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2004
Volume: 47
Issue: 3
First Page: 627
Last Page: 643
DOI: 10.1021/jm031019q

Target ChEMBL ID: CHEMBL218
ChEMBL Target Name: Cannabinoid CB1 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.001995	Kd	=	1.995	nM
0.03981	Kd	>	39.81	nM
0.03162	Kd	=	31.62	nM
0.03162	Kd	=	31.62	nM
0.005012	Kd	=	5.012	nM
0.001	Kd	=	1	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cannabinoid receptor 2

External ID: CHEMBL659744

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2004
Volume: 47
Issue: 3
First Page: 627
Last Page: 643
DOI: 10.1021/jm031019q

Target ChEMBL ID: CHEMBL253
ChEMBL Target Name: Cannabinoid CB2 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1	Ki	>	1000	nM
1	Ki	>	1000	nM
1	Ki	>	1000	nM
1	Ki	>	1000	nM
1	Ki	>	1000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cannabinoid receptor 1

External ID: CHEMBL657896

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2004
Volume: 47
Issue: 3
First Page: 627
Last Page: 643
DOI: 10.1021/jm031019q

Target ChEMBL ID: CHEMBL218
ChEMBL Target Name: Cannabinoid CB1 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.0359	Ki	=	35.9	nM
0.119	Ki	=	119	nM
0.293	Ki	=	293	nM
0.17	Ki	=	170	nM
0.197	Ki	=	197	nM
0.0526	Ki	=	52.6	nM

656827-75-7 靶点实验数据