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6563-66-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasma
External ID: CHEMBL3744231
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039

Target ChEMBL ID: CHEMBL613450
ChEMBL Target Name: Plasma
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
TT=24.4s
TT=25.96s
TT=27.45s
TT=25.1s
TT=23.33s
TT=29.03s
TT=23.08s
TT=24.98s
TT=25.48s
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasma
External ID: CHEMBL3744234
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039

Target ChEMBL ID: CHEMBL613450
ChEMBL Target Name: Plasma
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=6.84g/L
Activity=5.38g/L
Activity=5.92g/L
Activity=5.65g/L
Activity=5.94g/L
Activity=5.96g/L
Activity=6.13g/L
Activity=5.67g/L
Activity=5.74g/L
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasma
External ID: CHEMBL3744233
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039

Target ChEMBL ID: CHEMBL613450
ChEMBL Target Name: Plasma
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
APTT=36.65s
APTT=33.1s
APTT=30.48s
APTT=39.42s
APTT=38.28s
APTT=36s
APTT=34.18s
APTT=31.53s
APTT=34.49s
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasma
External ID: CHEMBL3744232
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039

Target ChEMBL ID: CHEMBL613450
ChEMBL Target Name: Plasma
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
PT=5.93s
PT=6.25s
PT=6.53s
PT=6.95s
PT=6.93s
PT=6.75s
PT=6.28s
PT=6.4s
PT=6.55s
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3744239
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039
Standard TypeStandard RelationStandard Value
LogP=0.8916
LogP=1.765
LogP=2.14
LogP=2.194
LogP=1.937
LogP=2.636
LogP=0.5924
LogP=1.646
LogP=1.593
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3744238
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039
Standard TypeStandard RelationStandard ValueStandard Units
Solubility=6.85ug.mL-1
Solubility=4.27ug.mL-1
Solubility=1.36ug.mL-1
Solubility=1.53ug.mL-1
Solubility=3.2ug.mL-1
Solubility=0.31ug.mL-1
Solubility=7.62ug.mL-1
Solubility=6.31ug.mL-1
Solubility=4.56ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3744237
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=64.6%
Inhibition=62.39%
Inhibition=44.25%
Inhibition=52.21%
Inhibition=48.23%
Inhibition=11.06%
Inhibition=53.1%
Inhibition=63.27%
Inhibition=56.19%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3744236
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=91.15%
Inhibition=88.05%
Inhibition=68.14%
Inhibition=76.11%
Inhibition=74.34%
Inhibition=20.35%
Inhibition=79.2%
Inhibition=89.38%
Inhibition=82.3%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3744241
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039
Standard TypeStandard RelationStandard Value
LogP=0.4799
LogP=1.018
LogP=1.863
LogP=1.809
LogP=1.396
LogP=2.271
LogP=-0.0513
LogP=0.7846
LogP=1.034
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3744240
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 106
First Page: 95
Last Page: 105
DOI: 10.1016/j.ejmech.2015.10.039
Standard TypeStandard RelationStandard Value
LogP=0.772
LogP=1.681
LogP=2.094
LogP=2.135
LogP=1.787
LogP=2.549
LogP=0.3647
LogP=1.409
LogP=1.537