HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Methionine aminopeptidase

External ID: CHEMBL853287

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 24
First Page: 5386
Last Page: 5391
DOI: 10.1016/j.bmcl.2005.09.019

Target ChEMBL ID: CHEMBL3423
ChEMBL Target Name: Methionine aminopeptidase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
12.1	IC50	=	12100	nM
13.6	IC50	=	13600	nM
0.558	IC50	=	558	nM
6.92	IC50	=	6920	nM
1.08	IC50	=	1080	nM
3.65	IC50	=	3650	nM
47.6	IC50	=	47600	nM
0.368	IC50	=	368	nM
1.11	IC50	=	1110	nM
0.642	IC50	=	642	nM
33.5	IC50	=	33500	nM
9.45	IC50	=	9450	nM
4.71	IC50	=	4710	nM
0.784	IC50	=	784	nM
3.47	IC50	=	3470	nM
1.32	IC50	=	1320	nM
15.9	IC50	=	15900	nM
6.56	IC50	=	6560	nM
0.469	IC50	=	469	nM
0.511	IC50	=	511	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Methionine aminopeptidase

External ID: CHEMBL853286

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 24
First Page: 5386
Last Page: 5391
DOI: 10.1016/j.bmcl.2005.09.019

Target ChEMBL ID: CHEMBL3423
ChEMBL Target Name: Methionine aminopeptidase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
180	IC50	=	180000	nM	Outside typical range
200	IC50	>	200000	nM	Outside typical range
120	IC50	=	120000	nM	Outside typical range
127	IC50	=	127000	nM	Outside typical range
120	IC50	=	120000	nM	Outside typical range
93.5	IC50	=	93500	nM
57.3	IC50	=	57300	nM
170	IC50	=	170000	nM	Outside typical range
59.5	IC50	=	59500	nM
24.1	IC50	=	24100	nM
42.5	IC50	=	42500	nM
103	IC50	=	103000	nM	Outside typical range
98.9	IC50	=	98900	nM
77.3	IC50	=	77300	nM
160	IC50	=	160000	nM	Outside typical range
44.3	IC50	=	44300	nM
71.4	IC50	=	71400	nM
77.1	IC50	=	77100	nM
4.61	IC50	=	4610	nM
138	IC50	=	138000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Methionine aminopeptidase

External ID: CHEMBL853290

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 24
First Page: 5386
Last Page: 5391
DOI: 10.1016/j.bmcl.2005.09.019

Target ChEMBL ID: CHEMBL3423
ChEMBL Target Name: Methionine aminopeptidase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
200	IC50	>	200000	nM	Outside typical range
200	IC50	>	200000	nM	Outside typical range
200	IC50	>	200000	nM	Outside typical range
190	IC50	=	190000	nM	Outside typical range
178	IC50	=	178000	nM	Outside typical range
111	IC50	=	111000	nM	Outside typical range
97.7	IC50	=	97700	nM
191	IC50	=	191000	nM	Outside typical range
150	IC50	=	150000	nM	Outside typical range
36.2	IC50	=	36200	nM
33.7	IC50	=	33700	nM
169	IC50	=	169000	nM	Outside typical range
193	IC50	=	193000	nM	Outside typical range
177	IC50	=	177000	nM	Outside typical range
200	IC50	>	200000	nM	Outside typical range
31.1	IC50	=	31100	nM
200	IC50	>	200000	nM	Outside typical range
58	IC50	=	58000	nM
0.793	IC50	=	793	nM
116	IC50	=	116000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Methionine aminopeptidase

External ID: CHEMBL853289

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 24
First Page: 5386
Last Page: 5391
DOI: 10.1016/j.bmcl.2005.09.019

Target ChEMBL ID: CHEMBL3423
ChEMBL Target Name: Methionine aminopeptidase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
200	IC50	>	200000	nM	Outside typical range
200	IC50	>	200000	nM	Outside typical range
200	IC50	>	200000	nM	Outside typical range
153	IC50	=	153000	nM	Outside typical range
175	IC50	=	175000	nM	Outside typical range
113	IC50	=	113000	nM	Outside typical range
56.3	IC50	=	56300	nM
197	IC50	=	197000	nM	Outside typical range
28.5	IC50	=	28500	nM
34.5	IC50	=	34500	nM
67.5	IC50	=	67500	nM
163	IC50	=	163000	nM	Outside typical range
171	IC50	=	171000	nM	Outside typical range
117	IC50	=	117000	nM	Outside typical range
194	IC50	=	194000	nM	Outside typical range
38.4	IC50	=	38400	nM
137	IC50	=	137000	nM	Outside typical range
5.78	IC50	=	5780	nM
5.9	IC50	=	5900	nM
141	IC50	=	141000	nM	Outside typical range

65172-75-0 靶点实验数据