HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_2803_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	Ki	Target Accession(s)	Ligand	Target
Ki	40.95	40950	P14902	BDBM24815	Indoleamine 2,3-dioxygenase 1
Ki	33.97	33970	P14902	BDBM24816	Indoleamine 2,3-dioxygenase 1
Ki	149.35	149350	P14902	BDBM24822	Indoleamine 2,3-dioxygenase 1
Ki	1267	1267000	P14902	BDBM24823	Indoleamine 2,3-dioxygenase 1
Ki	363.6	363600	P14902	BDBM24826	Indoleamine 2,3-dioxygenase 1
Ki	17.15	17150	P14902	BDBM24827	Indoleamine 2,3-dioxygenase 1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Indoleamine 2,3-dioxygenase 1

External ID: CHEMBL865155

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2006
Volume: 49
Issue: 2
First Page: 684
Last Page: 692
DOI: 10.1021/jm0508888

Target ChEMBL ID: CHEMBL4685
ChEMBL Target Name: Indoleamine 2,3-dioxygenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment	Data Validity Comment
33.97	Ki	=	33970	nM
62.36	Ki	=	62360	nM
149.35	Ki	=	149350	nM		Outside typical range
	Ki				Not Active

6392-77-4 靶点实验数据