HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Entamoeba histolytica

External ID: CHEMBL968129

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2000
Volume: 63
Issue: 12
First Page: 1638
Last Page: 1640
DOI: 10.1021/np000144r

Target ChEMBL ID: CHEMBL612853
ChEMBL Target Name: Entamoeba histolytica
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Entamoeba histolytica

External ID: CHEMBL968128

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2000
Volume: 63
Issue: 12
First Page: 1638
Last Page: 1640
DOI: 10.1021/np000144r

Target ChEMBL ID: CHEMBL612853
ChEMBL Target Name: Entamoeba histolytica
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL2351376

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2013
Volume: 76
Issue: 3
First Page: 311
Last Page: 315
DOI: 10.1021/np300638f

Standard Type	Standard Relation	Standard Value	Standard Units
Delta Tm	=	3.5	degrees C

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sortase

External ID: CHEMBL5228672

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2021
Volume: 64
Issue: 18.0
First Page: 13097
Last Page: 13130
DOI: 10.1021/acs.jmedchem.1c00386

Target ChEMBL ID: CHEMBL5362
ChEMBL Target Name: Sortase A
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
IC50	=	8.7	ug.mL-1
IC50	=	11.5	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Leishmania donovani

External ID: CHEMBL2351389

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2013
Volume: 76
Issue: 3
First Page: 311
Last Page: 315
DOI: 10.1021/np300638f

Target ChEMBL ID: CHEMBL367
ChEMBL Target Name: Leishmania donovani
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	IC50				Not Determined
17	IC50	=	17000	nM
0.29	IC50	=	290	nM
0.1	IC50	=	100	nM
0.2	IC50	=	200	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Vero

External ID: CHEMBL2351387

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2013
Volume: 76
Issue: 3
First Page: 311
Last Page: 315
DOI: 10.1021/np300638f

Target ChEMBL ID: CHEMBL391
ChEMBL Target Name: Vero
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment	Data Validity Comment
	IC50				Not Determined
200	IC50	>	200000	nM		Outside typical range
39	IC50	=	39000	nM
18	IC50	=	18000	nM
8.8	IC50	=	8800	nM

633-66-9 靶点实验数据