HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：U-937

External ID: CHEMBL1101674

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 3
First Page: 1113
Last Page: 1118
DOI: 10.1016/j.ejmech.2009.12.010

Target ChEMBL ID: CHEMBL612794
ChEMBL Target Name: U-937
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
97.7237	IC50	=	97723.72	nM
562.341	IC50	=	562341.33	nM	Outside typical range
131.826	IC50	=	131825.67	nM	Outside typical range
416.869	IC50	=	416869.38	nM	Outside typical range
213.796	IC50	=	213796.21	nM	Outside typical range
74.131	IC50	=	74131.02	nM
83.1764	IC50	=	83176.38	nM
10.4713	IC50	=	10471.29	nM
11.4815	IC50	=	11481.54	nM
7.76247	IC50	=	7762.47	nM
257.04	IC50	=	257039.58	nM	Outside typical range
6.76083	IC50	=	6760.83	nM
13.8038	IC50	=	13803.84	nM
6.60693	IC50	=	6606.93	nM
3.46737	IC50	=	3467.37	nM
0.77625	IC50	=	776.25	nM
0.77625	IC50	=	776.25	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：U-937

External ID: CHEMBL917840

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2007
Volume: 15
Issue: 2
First Page: 931
Last Page: 938
DOI: 10.1016/j.bmc.2006.10.035

Target ChEMBL ID: CHEMBL612794
ChEMBL Target Name: U-937
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
53.4	IC50	=	53400	nM
98.4	IC50	=	98400	nM
565	IC50	=	565000	nM	Outside typical range
132	IC50	=	132000	nM	Outside typical range
420	IC50	=	420000	nM	Outside typical range
214	IC50	=	214000	nM	Outside typical range
74.8	IC50	=	74800	nM
83	IC50	=	83000	nM
10.5	IC50	=	10500	nM
11.6	IC50	=	11600	nM
7.85	IC50	=	7850	nM
257	IC50	=	257000	nM	Outside typical range
17.1	IC50	=	17100	nM
6.76	IC50	=	6760	nM
76.5	IC50	=	76500	nM
13.7	IC50	=	13700	nM
2	IC50	=	2000	nM

6326-79-0 靶点实验数据