HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL633738

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1985
Volume: 28
Issue: 3
First Page: 333
Last Page: 346
DOI: 10.1021/jm00381a013

Standard Type	Standard Relation	Standard Value
LogP	=	-1.05
LogP	=	0.9
LogP	=	-0.24
LogP	=	0.62
LogP	=	0.7
LogP	=	0.18
LogP	=	0.48
LogP	=	-0.13
LogP	=	-0.24
LogP	=	-0.71
LogP	=	-0.3
LogP	=	0.75
LogP	=	2.99
LogP	=	2.46
LogP	=	2.27
LogP	=	1.85
LogP	=	0.18
LogP	=	-0.34
LogP	=	2.49
LogP	=	0.29

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Taste receptor type 2 member 38

External ID: CHEMBL4419135

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL4523248
ChEMBL Target Name: Taste receptor type 2 member 38
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	Activity	=	100	uM
30	Activity	=	30	uM
300	Activity	=	300	uM
0.3	Activity	=	0.3	uM
0.3	Activity	=	0.3	uM
0.15	Activity	=	0.15	uM
3	Activity	=	3	uM
2	Activity	=	2	uM
100	Activity	=	100	uM
10	Activity	=	10	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Taste receptor type 2 member 38

External ID: CHEMBL4419136

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL4523248
ChEMBL Target Name: Taste receptor type 2 member 38
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: SureChEMBL Patent Bioactivity Data

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment	Data Validity Comment
	EC50				Not Determined
260	EC50	=	260000	nM		Outside typical range
2000	EC50	=	2000000	nM		Outside typical range
2	EC50	=	2000	nM
2	EC50	=	2000	nM
0.5	EC50	=	500	nM
18	EC50	=	18000	nM
15	EC50	=	15000	nM
600	EC50	=	600000	nM		Outside typical range
55	EC50	=	55000	nM

625-53-6 靶点实验数据