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61418-22-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:DNA-dependent protein kinase catalytic subunit
External ID: CHEMBL1118579
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2010
Volume: 20
Issue: 12
First Page: 3649
Last Page: 3653
DOI: 10.1016/j.bmcl.2010.04.102

Target ChEMBL ID: CHEMBL3142
ChEMBL Target Name: DNA-dependent protein kinase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
4.8IC50=4800nM
5.4IC50=5400nM
0.03IC50=30nM
0.18IC50=180nM
1.2IC50=1200nM
1.6IC50=1600nM
0.68IC50=680nM