HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B

External ID: CHEMBL733082

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2000
Volume: 43
Issue: 25
First Page: 4747
Last Page: 4758
DOI: 10.1021/jm001028o

Target ChEMBL ID: CHEMBL2993
ChEMBL Target Name: Monoamine oxidase B
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.00257	IC50	=	2.57	nM
0.005623	IC50	=	5.623	nM
0.004365	IC50	=	4.365	nM
0.001148	IC50	=	1.148	nM
0.12589	IC50	=	125.89	nM
0.00871	IC50	=	8.71	nM
6.76083	IC50	=	6760.83	nM
0.007413	IC50	=	7.413	nM
0.003467	IC50	=	3.467	nM
0.003715	IC50	=	3.715	nM
1.04713	IC50	=	1047.13	nM
1.04713	IC50	=	1047.13	nM
0.05012	IC50	=	50.12	nM
2.5704	IC50	=	2570.4	nM
58.8844	IC50	=	58884.37	nM
0.23442	IC50	=	234.42	nM
0.38905	IC50	=	389.05	nM
0.01148	IC50	=	11.48	nM
0.63096	IC50	=	630.96	nM
16.9824	IC50	=	16982.44	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Polyunsaturated fatty acid 5-lipoxygenase

External ID: CHEMBL2157131

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2012
Volume: 55
Issue: 13
First Page: 5989
Last Page: 6001
DOI: 10.1021/jm300288g

Target ChEMBL ID: CHEMBL215
ChEMBL Target Name: Arachidonate 5-lipoxygenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.36	IC50	=	360	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Amine oxidase [flavin-containing] A

External ID: CHEMBL733246

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2000
Volume: 43
Issue: 25
First Page: 4747
Last Page: 4758
DOI: 10.1021/jm001028o

Target ChEMBL ID: CHEMBL3358
ChEMBL Target Name: Monoamine oxidase A
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	0	%

613-62-7 靶点实验数据