HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Acetylcholinesterase

External ID: CHEMBL829154

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2004
Volume: 47
Issue: 18
First Page: 4471
Last Page: 4482
DOI: 10.1021/jm049877p

Target ChEMBL ID: CHEMBL220
ChEMBL Target Name: Acetylcholinesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.02818	IC50	=	28.18	nM
8.12831	IC50	=	8128.31	nM
0.46774	IC50	=	467.74	nM
0.0871	IC50	=	87.1	nM
0.1	IC50	=	100	nM
0.01	IC50	=	10	nM
3.01995	IC50	=	3019.95	nM
0.07943	IC50	=	79.43	nM
10	IC50	=	10000	nM
0.50119	IC50	=	501.19	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Acetylcholinesterase

External ID: CHEMBL644110

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 1996
Volume: 6
Issue: 6
First Page: 737
Last Page: 742
DOI: 10.1016/0960-894X(96)00102-3

Target ChEMBL ID: CHEMBL220
ChEMBL Target Name: Acetylcholinesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.158	IC50	=	158	nM
1.26	IC50	=	1260	nM
100	IC50	>	100000	nM
3.72	IC50	=	3720	nM
13.51	IC50	=	13510	nM
1.7	IC50	=	1700	nM
9.2	IC50	=	9200	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Acetylcholinesterase

External ID: CHEMBL636823

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 1996
Volume: 6
Issue: 6
First Page: 737
Last Page: 742
DOI: 10.1016/0960-894X(96)00102-3

Target ChEMBL ID: CHEMBL3199
ChEMBL Target Name: Acetylcholinesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1.9	IC50	=	1900	nM
35.9	IC50	=	35900	nM
100	IC50	>	100000	nM
18	IC50	=	18000	nM
100	IC50	>	100000	nM
4.75	IC50	=	4750	nM
100	IC50	=	100000	nM

60811-50-9 靶点实验数据