HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Solute carrier family 15 member 2

External ID: CHEMBL1817008

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2011
Volume: 19
Issue: 15
First Page: 4544
Last Page: 4551
DOI: 10.1016/j.bmc.2011.06.027

Target ChEMBL ID: CHEMBL1743125
ChEMBL Target Name: Solute carrier family 15 member 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
3.80189	Ki	=	3801.89	nM
16	Ki	=	16000	nM
15.8489	Ki	=	15848.93	nM
14	Ki	=	14000	nM
14.1254	Ki	=	14125.38	nM
150	Ki	=	150000	nM
151.356	Ki	=	151356.12	nM
6	Ki	=	6000	nM
6.0256	Ki	=	6025.6	nM
8300	Ki	=	8300000	nM	Outside typical range
8317.64	Ki	=	8317637.71	nM	Outside typical range
12	Ki	=	12000	nM
12.0226	Ki	=	12022.64	nM
3300	Ki	=	3300000	nM	Outside typical range
3311.31	Ki	=	3311311.21	nM	Outside typical range
0.8	Ki	=	800	nM
0.79433	Ki	=	794.33	nM
950	Ki	=	950000	nM	Outside typical range
954.993	Ki	=	954992.59	nM	Outside typical range
420	Ki	=	420000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Solute carrier family 15 member 1

External ID: CHEMBL841787

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 13
First Page: 4410
Last Page: 4419
DOI: 10.1021/jm048982w

Target ChEMBL ID: CHEMBL4605
ChEMBL Target Name: Oligopeptide transporter small intestine isoform
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
410	Ki	=	410000	nM	Outside typical range
320	Ki	=	320000	nM	Outside typical range
2100	Ki	=	2100000	nM	Outside typical range
140	Ki	=	140000	nM	Outside typical range
21000	Ki	=	21000000	nM	Outside typical range
10000	Ki	>	10000000	nM	Outside typical range
12000	Ki	=	12000000	nM	Outside typical range
30000	Ki	>	30000000	nM	Outside typical range
2500	Ki	=	2500000	nM	Outside typical range
7200	Ki	=	7200000	nM	Outside typical range
30000	Ki	>	30000000	nM	Outside typical range
110	Ki	=	110000	nM	Outside typical range
390	Ki	=	390000	nM	Outside typical range
1000	Ki	=	1000000	nM	Outside typical range
860	Ki	=	860000	nM	Outside typical range
30000	Ki	>	30000000	nM	Outside typical range
10000	Ki	=	10000000	nM	Outside typical range
12000	Ki	=	12000000	nM	Outside typical range
300	Ki	=	300000	nM	Outside typical range
90	Ki	=	90000	nM

59005-82-2 靶点实验数据