HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL2432657

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2013
Volume: 76
Issue: 10
First Page: 1930
Last Page: 1936
DOI: 10.1021/np4005163

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	2.36	equiv
Activity	=	0.56	equiv
Activity	=	0.56	equiv
Activity	=	0.64	equiv

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL966631

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1979
Volume: 42
Issue: 5
First Page: 483
Last Page: 488
DOI: 10.1021/np50005a008

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	76	%
Activity	=	0	%
Activity	=	100	%
Activity	=	50	%
Activity	=	81	%
Activity	=	100	%
Activity	=	100	%
Activity	=	100	%
Activity	=	95	%
Activity	=	89	%
Activity	=	59	%
Activity	=	100	%
Activity	=	52	%
Activity	=	100	%
Activity	=	0	%
Activity	=	100	%
Activity	=	100	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Aromatase

External ID: CHEMBL5376029

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2017
Volume: 137
First Page: 365
Last Page: 438
DOI: 10.1016/j.ejmech.2017.05.041

Target ChEMBL ID: CHEMBL1978
ChEMBL Target Name: Cytochrome P450 19A1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
13.8038	IC50	=	13803.84	nM
36.9828	IC50	=	36982.82	nM
80.3526	IC50	=	80352.61	nM
0.69984	IC50	=	699.84	nM
88.7156	IC50	=	88715.6	nM
0.20989	IC50	=	209.89	nM
47.9733	IC50	=	47973.34	nM
16.9824	IC50	=	16982.44	nM
1	IC50	=	1000	nM
1.30017	IC50	=	1300.17	nM
0.74989	IC50	=	749.89	nM
0.52966	IC50	=	529.66	nM
4.19759	IC50	=	4197.59	nM
4.79733	IC50	=	4797.33	nM
2.39883	IC50	=	2398.83	nM
0.11092	IC50	=	110.92	nM
1.30017	IC50	=	1300.17	nM
2.95121	IC50	=	2951.21	nM
2.30144	IC50	=	2301.44	nM
1.64816	IC50	=	1648.16	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL2432656

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2013
Volume: 76
Issue: 10
First Page: 1930
Last Page: 1936
DOI: 10.1021/np4005163

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	2.4	equiv
Activity	=	0.44	equiv
Activity	=	0.56	equiv
Activity	=	0.88	equiv

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL966630

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1979
Volume: 42
Issue: 5
First Page: 483
Last Page: 488
DOI: 10.1021/np50005a008

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	0	%
Activity	=	0	%
Activity	=	46	%
Activity	=	0	%
Activity	=	0	%
Activity	=	0	%
Activity	=	0	%
Activity	=	0	%
Activity	=	0	%
Activity	=	0	%
Activity	=	0	%
Activity	=	0	%
Activity	=	100	%
Activity	=	0	%
Activity	=	0	%
Activity	=	39	%

57765-66-9 靶点实验数据