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57765-24-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL2378167
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 9
First Page: 2571
Last Page: 2574
DOI: 10.1016/j.bmcl.2013.02.114

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
25IC50>25000nM
6.22IC50=6220nM
100IC50>100000nM
100IC50>100000nM
83.57IC50=83570nM
57.72IC50=57720nM
73.09IC50=73090nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL2378169
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 9
First Page: 2571
Last Page: 2574
DOI: 10.1016/j.bmcl.2013.02.114

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
53.25IC50=53250nM
400IC50>400000nMOutside typical range
99.61IC50=99610nM
400IC50>400000nMOutside typical range
161.14IC50=161140nMOutside typical range
325.15IC50=325150nMOutside typical range
400IC50>400000nMOutside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL2378168
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 9
First Page: 2571
Last Page: 2574
DOI: 10.1016/j.bmcl.2013.02.114

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
20.44IC50=20440nM
39.76IC50=39760nM
100IC50>100000nM
100IC50>100000nM
100IC50>100000nM
100IC50>100000nM
48.74IC50=48740nM