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5632-13-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Lysyl oxidase homolog 2
External ID: CHEMBL3997541
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: ACS Med Chem Lett
Year: 2017
Volume: 8
Issue: 4
First Page: 423
Last Page: 427
DOI: 10.1021/acsmedchemlett.7b00014

Target ChEMBL ID: CHEMBL3714029
ChEMBL Target Name: Lysyl oxidase homolog 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
3.62IC50=3620nM
47IC50=47000nM
1.11IC50=1110nM
0.719IC50=719nM
3.54IC50=3540nM
1.22IC50=1220nM
0.066IC50=66nM
0.309IC50=309nM
100IC50>100000nM
1.18IC50=1180nM
0.67IC50=670nM
6.04IC50=6040nM
0.321IC50=321nM
8.21IC50=8210nM
31IC50>31000nM
100IC50>100000nM
0.902IC50=902nM
0.999IC50=999nM
0.385IC50=385nM
0.203IC50=203nM