HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL2341229

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	32	ug.mL-1
MIC	=	2	ug.mL-1
MIC	>	32	ug.mL-1
MIC	=	2	ug.mL-1
MIC	=	1	ug.mL-1
MIC	=	4	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Pseudomonas aeruginosa

External ID: CHEMBL2341228

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	8	ug.mL-1
MIC	=	1	ug.mL-1
MIC	>	32	ug.mL-1
MIC	=	4	ug.mL-1
MIC	=	0.5	ug.mL-1
MIC	=	2	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL2339329

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active
Inhibition	=	26	%
Inhibition				Not Active
Inhibition	=	12	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL2339328

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	8	ug.mL-1
MIC	=	4	ug.mL-1
MIC	>	32	ug.mL-1
MIC	=	2	ug.mL-1
MIC	=	2	ug.mL-1
MIC	=	4	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL2339327

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	>	32	ug.mL-1
MIC	=	4	ug.mL-1
MIC	>	32	ug.mL-1
MIC	=	2	ug.mL-1
MIC	=	2	ug.mL-1
MIC	=	4	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL2339333

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active
Inhibition	=	30	%
Inhibition	=	85	%
Inhibition	=	85	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Methionine aminopeptidase 1

External ID: CHEMBL2339332

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Target ChEMBL ID: CHEMBL2474
ChEMBL Target Name: Methionine aminopeptidase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Units	Activity Comment
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL2341706

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
t1/2				Not Determined
t1/2				Not Determined
t1/2				Not Determined
T1/2	=	58	hr
t1/2				Not Determined
T1/2	=	0.5	hr

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Methionine aminopeptidase 2

External ID: CHEMBL2339331

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Target ChEMBL ID: CHEMBL3922
ChEMBL Target Name: Methionine aminopeptidase 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active
Inhibition	=	7	%
Inhibition	=	22	%
Inhibition	=	13	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Prothrombin

External ID: CHEMBL2339330

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Target ChEMBL ID: CHEMBL204
ChEMBL Target Name: Thrombin
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Inhibition				Not Active
Inhibition				Not Active
Inhibition				Not Active
Inhibition	=	19	%
Inhibition				Not Active
Inhibition	=	8	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL2341705

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
t1/2				Not Determined
t1/2				Not Determined
t1/2				Not Determined
T1/2	=	116	hr
t1/2				Not Determined
T1/2	=	6	hr

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL2341700

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Standard Type	Activity Comment
Activity	Not Determined
Activity	Not Determined
Activity	Active
Activity	Not Active
Activity	Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL2341699

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2013
Volume: 21
Issue: 3
First Page: 795
Last Page: 804
DOI: 10.1016/j.bmc.2012.11.018

Standard Type	Activity Comment
Activity	Not Determined
Activity	Not Determined
Activity	Active
Activity	Active
Activity	Not Active
Activity	Not Active

563-70-2 靶点实验数据