HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HeLa

External ID: CHEMBL690911

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1991
Volume: 34
Issue: 8
First Page: 2414
Last Page: 2420
DOI: 10.1021/jm00112a016

Target ChEMBL ID: CHEMBL399
ChEMBL Target Name: HeLa
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
500	IC50	>	500000	nM	Outside typical range
200	IC50	=	200000	nM	Outside typical range
5	IC50	=	5000	nM
30	IC50	=	30000	nM
200	IC50	=	200000	nM	Outside typical range
20	IC50	=	20000	nM
500	IC50	>	500000	nM	Outside typical range
20	IC50	=	20000	nM
500	IC50	>	500000	nM	Outside typical range
125	IC50	=	125000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nucleic Acid

External ID: CHEMBL762469

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1991
Volume: 34
Issue: 8
First Page: 2414
Last Page: 2420
DOI: 10.1021/jm00112a016

Target ChEMBL ID: CHEMBL345
ChEMBL Target Name: Nucleic Acid
ChEMBL Target Type: NUCLEIC-ACID - Target is DNA, RNA or PNA
Relationship Type: M - Molecular target other than protein assigned
Confidence: Target assigned is molecular non-protein target

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
3.9	IC50	=	3900	nM
140	IC50	=	140000	nM	Outside typical range
4.5	IC50	=	4500	nM
2.6	IC50	=	2600	nM
4.3	IC50	=	4300	nM
2.8	IC50	=	2800	nM
4.5	IC50	=	4500	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Calf thymus DNA

External ID: CHEMBL660979

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1991
Volume: 34
Issue: 8
First Page: 2414
Last Page: 2420
DOI: 10.1021/jm00112a016

Target ChEMBL ID: CHEMBL612514
ChEMBL Target Name: Calf thymus DNA
ChEMBL Target Type: NUCLEIC-ACID - Target is DNA, RNA or PNA
Relationship Type: M - Molecular target other than protein assigned
Confidence: Target assigned is molecular non-protein target

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
17	IC50	=	17000	nM
15	IC50	=	15000	nM
220	IC50	=	220000	nM	Outside typical range
12	IC50	=	12000	nM
6.5	IC50	=	6500	nM
3.8	IC50	=	3800	nM
5.2	IC50	=	5200	nM
8	IC50	=	8000	nM
10	IC50	=	10000	nM
19.1	IC50	=	19100	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nucleic Acid

External ID: CHEMBL762625

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1991
Volume: 34
Issue: 8
First Page: 2414
Last Page: 2420
DOI: 10.1021/jm00112a016

Target ChEMBL ID: CHEMBL345
ChEMBL Target Name: Nucleic Acid
ChEMBL Target Type: NUCLEIC-ACID - Target is DNA, RNA or PNA
Relationship Type: M - Molecular target other than protein assigned
Confidence: Target assigned is molecular non-protein target

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
19.5	IC50	=	19500	nM
370	IC50	=	370000	nM	Outside typical range
16	IC50	=	16000	nM
5.4	IC50	=	5400	nM
27	IC50	=	27000	nM
10.7	IC50	=	10700	nM
30	IC50	=	30000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HeLa

External ID: CHEMBL690120

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1991
Volume: 34
Issue: 8
First Page: 2414
Last Page: 2420
DOI: 10.1021/jm00112a016

Target ChEMBL ID: CHEMBL399
ChEMBL Target Name: HeLa
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
IC50	nM	Not Determined

56-22-4 靶点实验数据