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552-72-7 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Neuronal acetylcholine receptor subunit alpha-7
External ID: CHEMBL748707
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1999
Volume: 42
Issue: 18
First Page: 3726
Last Page: 3731
DOI: 10.1021/jm990286m

Target ChEMBL ID: CHEMBL2094110
ChEMBL Target Name: Neuronal acetylcholine receptor
ChEMBL Target Type: PROTEIN COMPLEX GROUP - Target is a poorly defined protein complex, where subunit composition is unclear (e.g., GABA-A receptor)
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
10Ki>10000nM
0.005Ki=5nM
1.315Ki=1315nM
10Ki>10000nM
0.11Ki=110nM
1.085Ki=1085nM