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547-75-1 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasmodium falciparum
External ID: CHEMBL3592749
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=56%
Inhibition=85%
Inhibition=77%
Inhibition=67%
Inhibition=59%
Inhibition=54%
Inhibition=68%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Trypanosoma brucei brucei
External ID: CHEMBL3592640
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044

Target ChEMBL ID: CHEMBL612851
ChEMBL Target Name: Trypanosoma brucei brucei
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=20%
Inhibition=5%
Inhibition=11%
Inhibition=1%
Inhibition=2%
Inhibition=7%
Inhibition=15%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3592363
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
20.25IC50=20250nM
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
68.03IC50>68030nM
68.03IC50>68030nM
IC50Not Active
16.8IC50=16800nM
IC50Not Determined
IC50Not Determined
4.41IC50=4410nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasmodium falciparum
External ID: CHEMBL3592641
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=83%
Inhibition=100%
Inhibition=98%
Inhibition=97%
Inhibition=100%
Inhibition=92%
Inhibition=100%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Trypanosoma brucei brucei
External ID: CHEMBL3592364
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044

Target ChEMBL ID: CHEMBL612851
ChEMBL Target Name: Trypanosoma brucei brucei
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
21.2IC50=21200nM
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
62.18IC50=62180nM
68.03IC50>68030nM
IC50Not Determined
12.5IC50=12500nM
16.3IC50=16300nM
5.6IC50=5600nM
1.47IC50=1470nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasmodium falciparum
External ID: CHEMBL3592467
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
0.6327IC50=632.7nM
132.7IC50=132700nMOutside typical range
26.9IC50=26900nM
18.9IC50=18900nM
40.9IC50=40900nM
93.6IC50=93600nM
59.5IC50=59500nM
0.9626IC50=962.6nM
0.2925IC50=292.5nM
0.0362IC50=36.2nM
21IC50=21000nM
32.7IC50=32700nM
8.1IC50=8100nM
0.1967IC50=196.7nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3592638
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=6%
Inhibition=22%
Inhibition=27%
Inhibition=21%
Inhibition=9%
Inhibition=18%
Inhibition=12%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Trypanosoma brucei brucei
External ID: CHEMBL3592639
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044

Target ChEMBL ID: CHEMBL612851
ChEMBL Target Name: Trypanosoma brucei brucei
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=24%
Inhibition=100%
Inhibition=100%
Inhibition=94%
Inhibition=100%
Inhibition=64%
Inhibition=100%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3592637
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2015
Volume: 100
First Page: 10
Last Page: 17
DOI: 10.1016/j.ejmech.2015.05.044
Standard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
InhibitionNot Determined
Inhibition=98%
Inhibition=94%
Inhibition=22%
Inhibition=50%
InhibitionNot Determined
Inhibition=29%