HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 3

External ID: CHEMBL662691

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1999
Volume: 42
Issue: 25
First Page: 5169
Last Page: 5180
DOI: 10.1021/jm9910728

Target ChEMBL ID: CHEMBL2095180
ChEMBL Target Name: Carbonic anhydrase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Relation	Standard Value
Log K	=	7.09
Log K	=	6.69
Log K	=	7.08
Log K	=	8.08
Log K	=	7.53
Log K	=	8.88
Log K	=	8.49
Log K	=	8.3
Log K	=	7.53
Log K	=	4.41
Log K	=	8.75
Log K	=	8.77
Log K	=	8.5
Log K	=	7.98
Log K	=	5.28
Log K	=	4.8
Log K	=	9.39
Log K	=	9.11
Log K	=	9.39
Log K	=	6.21

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 2

External ID: CHEMBL828405

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 4
First Page: 923
Last Page: 930
DOI: 10.1016/j.bmcl.2004.12.056

Target ChEMBL ID: CHEMBL205
ChEMBL Target Name: Carbonic anhydrase II
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value
Log K	=	7.09
Log K	=	6.69
Log K	=	7.08
Log K	=	8.08
Log K	=	7.53
Log K	=	8.88
Log K	=	8.49
Log K	=	8.3
Log K	=	7.53
Log K	=	4.41
Log K	=	8.75
Log K	=	8.77
Log K	=	8.5
Log K	=	7.98
Log K	=	5.28
Log K	=	4.8
Log K	=	9.39
Log K	=	9.11
Log K	=	9.39
Log K	=	6.21

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL829145

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 4
First Page: 923
Last Page: 930
DOI: 10.1016/j.bmcl.2004.12.056

Standard Type	Standard Relation	Standard Value
LogP	=	0.69
LogP	=	0.21
LogP	=	-0.31
LogP	=	0.51
LogP	=	0.03
LogP	=	2.05
LogP	=	1.05
LogP	=	2.45
LogP	=	1.31
LogP	=	0.45
LogP	=	1.54
LogP	=	1.75
LogP	=	1.17
LogP	=	0.64
LogP	=	1.49
LogP	=	0.72
LogP	=	2.71
LogP	=	2.34
LogP	=	3.23
LogP	=	1.11

5446-77-5 靶点实验数据