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54283-75-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL4394289
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2019
Volume: 172
First Page: 16
Last Page: 25
DOI: 10.1016/j.ejmech.2019.03.048
Standard TypeStandard Text Value
Drug metabolismMetabolite_Detected
Drug metabolismMetabolite_Detected
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL4394292
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2019
Volume: 172
First Page: 16
Last Page: 25
DOI: 10.1016/j.ejmech.2019.03.048
Standard TypeStandard Text Value
Drug metabolismMetabolite_Detected
Drug metabolismMetabolite_Detected
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL4828641
Protocol: N/A
Comment: Journal: ACS Med Chem Lett
Year: 2021
Volume: 12
Issue: 11.0
First Page: 1669
Last Page: 1677
DOI: 10.1021/acsmedchemlett.1c00252
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
42.8IC50=42800nM
75IC50>75000nM
75IC50>75000nM
60IC50>60000nM
75IC50>75000nM
75IC50>75000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:HaCaT
External ID: CHEMBL4828644
Protocol: N/A
Comment: Journal: ACS Med Chem Lett
Year: 2021
Volume: 12
Issue: 11.0
First Page: 1669
Last Page: 1677
DOI: 10.1021/acsmedchemlett.1c00252

Target ChEMBL ID: CHEMBL614392
ChEMBL Target Name: HaCaT
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
125IC50>125000nMOutside typical range
IC50Not Determined
IC50Not Determined
60IC50>60000nM
150IC50>150000nMOutside typical range
150IC50>150000nMOutside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:B16-F10
External ID: CHEMBL4828642
Protocol: N/A
Comment: Journal: ACS Med Chem Lett
Year: 2021
Volume: 12
Issue: 11.0
First Page: 1669
Last Page: 1677
DOI: 10.1021/acsmedchemlett.1c00252

Target ChEMBL ID: CHEMBL612656
ChEMBL Target Name: B16-F10
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
75IC50>75000nM
75IC50>75000nM
75IC50>75000nM
60IC50>60000nM
75IC50>75000nM
75IC50>75000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:A-375
External ID: CHEMBL4828643
Protocol: N/A
Comment: Journal: ACS Med Chem Lett
Year: 2021
Volume: 12
Issue: 11.0
First Page: 1669
Last Page: 1677
DOI: 10.1021/acsmedchemlett.1c00252

Target ChEMBL ID: CHEMBL613859
ChEMBL Target Name: A-375
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
IC50Not Determined
75IC50>75000nM
75IC50>75000nM
IC50Not Determined
IC50Not Determined
IC50Not Determined