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53-50-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Tubulin beta-2B chain
External ID: CHEMBL815060
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 23
First Page: 3836
Last Page: 3841
DOI: 10.1021/jm970323e

Target ChEMBL ID: CHEMBL2094134
ChEMBL Target Name: Tubulin
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: D - Direct protein target assigned
Confidence: Multiple direct protein targets may be assigned
Standard TypeStandard RelationStandard Value
Activity=1
Activity=0.79
Activity=1.5
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Tubulin beta-2B chain
External ID: CHEMBL820774
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 23
First Page: 3836
Last Page: 3841
DOI: 10.1021/jm970323e

Target ChEMBL ID: CHEMBL3394
ChEMBL Target Name: Tubulin beta chain
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
7.2IC50=7200nM
29800IC50=29800000nMOutside typical range
5900IC50=5900000nMOutside typical range