HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cytochrome P450 1B1

External ID: CHEMBL3877873

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2016
Volume: 26
Issue: 21
First Page: 5272
Last Page: 5276
DOI: 10.1016/j.bmcl.2016.09.046

Target ChEMBL ID: CHEMBL4878
ChEMBL Target Name: Cytochrome P450 1B1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	89.2	%
Inhibition	=	4.4	%
Inhibition
Inhibition	=	8.6	%
Inhibition	=	13.2	%
Inhibition	=	40	%
Inhibition	=	9.7	%
Inhibition	=	1	%
Inhibition	=	22.6	%
Inhibition	=	7.5	%
Inhibition	=	2	%
Inhibition	=	28.7	%
Inhibition	=	11.3	%
Inhibition	=	1	%
Inhibition	=	29	%
Inhibition	=	0.9	%
Inhibition	=	11.4	%
Inhibition	=	16.2	%
Inhibition	=	11.5	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Sulfotransferase

External ID: CHEMBL681340

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1986
Volume: 29
Issue: 5
First Page: 692
Last Page: 698
DOI: 10.1021/jm00155a019

Target ChEMBL ID: CHEMBL3811
ChEMBL Target Name: Estrogen sulfotransferase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
7.51	Ki	=	7510	nM
10.51	Ki	=	10510	nM

53-45-2 靶点实验数据