HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Histone acetyltransferase KAT2B

External ID: CHEMBL3227012

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: MedChemComm
Year: 2013
Volume: 4
Issue: 4
First Page: 737
Last Page: 740
DOI: 10.1039/C3MD20376J

Target ChEMBL ID: CHEMBL5500
ChEMBL Target Name: Histone acetyltransferase PCAF
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
5.9	IC50	=	5900	nM
10.8	IC50	=	10800	nM
215.1	IC50	=	215100	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Human immunodeficiency virus 1

External ID: CHEMBL3227331

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: MedChemComm
Year: 2013
Volume: 4
Issue: 4
First Page: 737
Last Page: 740
DOI: 10.1039/C3MD20376J

Target ChEMBL ID: CHEMBL378
ChEMBL Target Name: Human immunodeficiency virus 1
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
4.16	EC50	=	4160	nM
11.25	EC50	=	11250	nM
14.31	EC50	=	14310	nM
2.22	EC50	=	2220	nM
0.56	EC50	=	560	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：C8166

External ID: CHEMBL3227368

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: MedChemComm
Year: 2013
Volume: 4
Issue: 4
First Page: 737
Last Page: 740
DOI: 10.1039/C3MD20376J

Target ChEMBL ID: CHEMBL614533
ChEMBL Target Name: C8166
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10.09	CC50	=	10090	nM
20.66	CC50	=	20660	nM
17.71	CC50	=	17710	nM
13.76	CC50	=	13760	nM
6.27	CC50	=	6270	nM

52289-07-3 靶点实验数据