HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL2021314

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	1	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	=	128	ug.mL-1
MIC	=	64	ug.mL-1
MIC	>	128	ug.mL-1
MIC	=	32	ug.mL-1
MIC	=	64	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL887260

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2007
Volume: 42
Issue: 4
First Page: 447
Last Page: 455
DOI: 10.1016/j.ejmech.2006.09.008

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	7.1	%
Inhibition	=	15.16	%
Inhibition	=	6.03	%
Inhibition	=	6.89	%
Inhibition	=	10.09	%
Inhibition	=	3.1	%
Inhibition	=	3.43	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Moraxella catarrhalis

External ID: CHEMBL2021317

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL614429
ChEMBL Target Name: Moraxella catarrhalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	<	0.125	ug.mL-1
MIC	=	128	ug.mL-1
MIC	=	16	ug.mL-1
MIC	=	128	ug.mL-1
MIC	=	16	ug.mL-1
MIC	=	128	ug.mL-1
MIC	=	8	ug.mL-1
MIC	=	2	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Haemophilus influenzae

External ID: CHEMBL2021318

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL355
ChEMBL Target Name: Haemophilus influenzae
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	1	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	=	64	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	=	32	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus pneumoniae

External ID: CHEMBL2021315

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL347
ChEMBL Target Name: Streptococcus pneumoniae
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	<	0.125	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus pyogenes

External ID: CHEMBL2021316

Protocol: N/A

Comment: Journal: Bioorg Med Chem
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL356
ChEMBL Target Name: Streptococcus pyogenes
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	<	0.125	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Jurkat

External ID: CHEMBL2021321

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL397
ChEMBL Target Name: Jurkat
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	IC50	>	100000	nM
78	IC50	=	78000	nM
75	IC50	=	75000	nM
83	IC50	=	83000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL2021319

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	2	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1
MIC	>	128	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HepG2

External ID: CHEMBL2021320

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2012
Volume: 20
Issue: 10
First Page: 3180
Last Page: 3185
DOI: 10.1016/j.bmc.2012.03.074

Target ChEMBL ID: CHEMBL395
ChEMBL Target Name: HepG2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	IC50	>	100000	nM
100	IC50	>	100000	nM
93	IC50	=	93000	nM
90	IC50	=	90000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL887261

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2007
Volume: 42
Issue: 4
First Page: 447
Last Page: 455
DOI: 10.1016/j.ejmech.2006.09.008

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	14.52	%
Activity	=	25.82	%
Activity	=	15.07	%
Activity	=	14.51	%
Activity	=	16.1	%
Activity	=	7.1	%
Activity	=	5.06	%

51584-72-6 靶点实验数据