HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Indoleamine 2,3-dioxygenase 1

External ID: CHEMBL3767626

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2016
Volume: 108
First Page: 564
Last Page: 576
DOI: 10.1016/j.ejmech.2015.12.028

Target ChEMBL ID: CHEMBL4685
ChEMBL Target Name: Indoleamine 2,3-dioxygenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.81	IC50	=	810	nM
71	IC50	=	71000	nM
6	IC50	=	6000	nM
1.3	IC50	=	1300	nM
1.6	IC50	=	1600	nM
82	IC50	=	82000	nM
0.34	IC50	=	340	nM
0.41	IC50	=	410	nM
0.57	IC50	=	570	nM
0.63	IC50	=	630	nM
10	IC50	=	10000	nM
10	IC50	=	10000	nM
3.4	IC50	=	3400	nM
1.6	IC50	=	1600	nM
9.5	IC50	=	9500	nM
20	IC50	=	20000	nM
0.73	IC50	=	730	nM
0.32	IC50	=	320	nM
0.3	IC50	=	300	nM
1	IC50	=	1000	nM

51572-91-9 靶点实验数据