HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Delta-type opioid receptor

External ID: CHEMBL1909180

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL236
ChEMBL Target Name: Delta-type opioid receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric oxide synthase, inducible

External ID: CHEMBL1909179

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL3464
ChEMBL Target Name: Nitric oxide synthase, inducible
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mu-type opioid receptor

External ID: CHEMBL1909182

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL233
ChEMBL Target Name: Mu-type opioid receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cyclin-dependent kinase 2

External ID: CHEMBL5062802

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL301
ChEMBL Target Name: Cyclin-dependent kinase 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: EUbOPEN Chemogenomic Library

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Delta TM	=	0.1409	C	Thermal Shift Assay
Delta TM	=	-0.01457	C	Thermal Shift Assay
Delta TM	=	-0.19	C
Delta TM	=	1.16	C	Thermal Shift Assay
Delta TM	=	1.921	C	Thermal Shift Assay
Delta TM	=	-0.3406	C	Thermal Shift Assay
Delta TM	=	0.6	C	Thermal Shift Assay
Delta TM	=	-0.1127	C	Thermal Shift Assay
Delta TM	=	-1.169	C	Thermal Shift Assay
Delta TM	=	0.82	C
Delta TM	=	0.31	C	Thermal Shift Assay
Delta TM	=	-0.02	C	Thermal Shift Assay
Delta TM	=	0.46	C	Thermal Shift Assay
Delta TM	=	-1.475	C	Thermal Shift Assay
Delta TM	=	-0.6313	C	Thermal Shift Assay
Delta TM	=	0	C	Thermal Shift Assay
Delta TM	=	-0.6762	C	Thermal Shift Assay
Delta TM	=	1.46	C	Thermal Shift Assay
Delta TM	=	0.98	C	Thermal Shift Assay
Delta TM	=	0.83	C	Thermal Shift Assay

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Kappa-type opioid receptor

External ID: CHEMBL1909181

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL237
ChEMBL Target Name: Kappa-type opioid receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909184

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909183

Protocol: N/A

Comment: Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：cGMP-specific 3',5'-cyclic phosphodiesterase

External ID: CHEMBL1909186

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL1827
ChEMBL Target Name: cGMP-specific 3',5'-cyclic phosphodiesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
11.476	IC50	=	11476		nM
	Ki					Note: corresponding IC50 reported as Active
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909185

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
11.59	IC50	=	11590		nM
	Ki					Note: corresponding IC50 reported as Active
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M3

External ID: CHEMBL1909172

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL245
ChEMBL Target Name: Muscarinic acetylcholine receptor M3
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
2.39E-4	Ki	=	0.239		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M2

External ID: CHEMBL1909171

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL211
ChEMBL Target Name: Muscarinic acetylcholine receptor M2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M5

External ID: CHEMBL1909174

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL2035
ChEMBL Target Name: Muscarinic acetylcholine receptor M5
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
0.32	IC50	=	320		nM
0.23	Ki	=	230		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Muscarinic acetylcholine receptor M4

External ID: CHEMBL1909173

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL1821
ChEMBL Target Name: Muscarinic acetylcholine receptor M4
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
2.066	IC50	=	2066		nM
0.288	Ki	=	288		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Neuropeptide Y receptor type 2

External ID: CHEMBL1909176

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL4018
ChEMBL Target Name: Neuropeptide Y receptor type 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Neuropeptide Y receptor type 1

External ID: CHEMBL1909175

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL4777
ChEMBL Target Name: Neuropeptide Y receptor type 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta

External ID: CHEMBL5065861

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL262
ChEMBL Target Name: Glycogen synthase kinase-3 beta
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Delta TM	=	-0.6111	C	Thermal Shift Assay

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric oxide synthase 1

External ID: CHEMBL1909178

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL3048
ChEMBL Target Name: Nitric oxide synthase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909177

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
0.004123	Ki	=	4.123		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Interstitial collagenase

External ID: CHEMBL1909196

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL332
ChEMBL Target Name: Interstitial collagenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Neutrophil elastase

External ID: CHEMBL1909195

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL248
ChEMBL Target Name: Neutrophil elastase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Protein kinase C alpha type

External ID: CHEMBL1909198

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL299
ChEMBL Target Name: Protein kinase C alpha type
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Matrix metalloproteinase-9

External ID: CHEMBL1909197

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL321
ChEMBL Target Name: Matrix metalloproteinase-9
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mitogen-activated protein kinase 1

External ID: CHEMBL1909200

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL4040
ChEMBL Target Name: Mitogen-activated protein kinase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mitogen-activated protein kinase 3

External ID: CHEMBL1909199

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL3385
ChEMBL Target Name: Mitogen-activated protein kinase 3
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Protein phosphatase 3 catalytic subunit alpha

External ID: CHEMBL1909202

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL4445
ChEMBL Target Name: Protein phosphatase 3 catalytic subunit alpha
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mitogen-activated protein kinase 14

External ID: CHEMBL1909201

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL260
ChEMBL Target Name: Mitogen-activated protein kinase 14
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
0.159	IC50	=	159		nM
	Ki					Note: corresponding IC50 reported as Active
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909188

Protocol: N/A

Comment: Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Platelet-activating factor receptor

External ID: CHEMBL1909187

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL250
ChEMBL Target Name: Platelet-activating factor receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Voltage-gated inwardly rectifying potassium channel KCNH2

External ID: CHEMBL1909190

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL240
ChEMBL Target Name: Voltage-gated inwardly rectifying potassium channel KCNH2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909189

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Angiotensin-converting enzyme

External ID: CHEMBL1909192

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL4074
ChEMBL Target Name: Angiotensin-converting enzyme
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Progesterone receptor

External ID: CHEMBL1909191

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL1909044
ChEMBL Target Name: Progesterone receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cathepsin G

External ID: CHEMBL1909194

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL4071
ChEMBL Target Name: Cathepsin G
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Caspase-1

External ID: CHEMBL1909193

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL4801
ChEMBL Target Name: Caspase-1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Acetylcholinesterase

External ID: CHEMBL1909212

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL220
ChEMBL Target Name: Acetylcholinesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
5.847	IC50	=	5847		nM
	Ki					Note: corresponding IC50 reported as Active
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
6.9071	IC50	=	6907.1		nM
	Ki					Note: corresponding IC50 reported as Active
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 2A

External ID: CHEMBL1909211

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL224
ChEMBL Target Name: 5-hydroxytryptamine receptor 2A
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
2.991	Ki	=	2991		nM
10.469	IC50	=	10469		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
2.286	IC50	=	2286		nM
0.653	Ki	=	653		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
0.075	IC50	=	75		nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Adenosine receptor A2a

External ID: CHEMBL1909214

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL251
ChEMBL Target Name: Adenosine receptor A2a
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Adenosine receptor A1

External ID: CHEMBL1909213

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL226
ChEMBL Target Name: Adenosine receptor A1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
2.95	IC50	=	2950		nM
1.721	Ki	=	1721		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909084

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
5.923	IC50	=	5923		nM
2.026	Ki	=	2026		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Adenosine receptor A3

External ID: CHEMBL1909215

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL256
ChEMBL Target Name: Adenosine receptor A3
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Alpha-1B adrenergic receptor

External ID: CHEMBL1909086

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL315
ChEMBL Target Name: Alpha-1B adrenergic receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
0.119	IC50	=	119		nM
0.066	Ki	=	66		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Alpha-1A adrenergic receptor

External ID: CHEMBL1909085

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL319
ChEMBL Target Name: Alpha-1A adrenergic receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
0.224	IC50	=	224		nM
0.091	Ki	=	91		nM
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Tyrosine-protein kinase Fyn

External ID: CHEMBL1909204

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL1841
ChEMBL Target Name: Tyrosine-protein kinase Fyn
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Epidermal growth factor receptor

External ID: CHEMBL1909203

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL203
ChEMBL Target Name: Epidermal growth factor receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Tyrosine-protein kinase Lck

External ID: CHEMBL1909206

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL258
ChEMBL Target Name: Tyrosine-protein kinase Lck
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
0.2938	IC50	=	293.8		nM
	Ki					Note: corresponding IC50 reported as Active
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2

External ID: CHEMBL4303805

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL4303835
ChEMBL Target Name: SARS-CoV-2
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: SARS-CoV-2 Screening Data

Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
Inhibition	=	-11.52	%	Outside typical range
Inhibition	=	5.09	%
Inhibition	=	-1.71	%
Inhibition	=	3.69	%
Inhibition	=	22.47	%
Inhibition	=	8.51	%
Inhibition	=	-6.86	%
Inhibition	=	-6.18	%
Inhibition	=	-2.07	%
Inhibition	=	3.91	%
Inhibition	=	-5.9	%
Inhibition	=	-2.45	%
Inhibition	=	-5.55	%
Inhibition	=	6.31	%
Inhibition	=	-1.08	%
Inhibition	=	12.7	%
Inhibition	=	0.37	%
Inhibition	=	8.88	%
Inhibition	=	11.63	%
Inhibition	=	-1.96	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Receptor tyrosine-protein kinase erbB-2

External ID: CHEMBL1909205

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL1824
ChEMBL Target Name: Receptor tyrosine-protein kinase erbB-2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
18.896	IC50	=	18896		nM
	Ki					Note: corresponding IC50 reported as Active
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1909208

Protocol: N/A

Comment: Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Receptor-type tyrosine-protein phosphatase C

External ID: CHEMBL1909207

Protocol: N/A

Comment: Target ChEMBL ID: CHEMBL3243
ChEMBL Target Name: Receptor-type tyrosine-protein phosphatase C
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Data Source: DrugMatrix

Standard Type	Standard Text Value	Activity Comment
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
IC50	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
Ki	Not Active	Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1B

External ID: CHEMBL1909210

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL3459
ChEMBL Target Name: 5-hydroxytryptamine receptor 1B
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Data Source: DrugMatrix

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Text Value	Standard Units	Activity Comment
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
4.72	IC50	=	4720		nM
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	IC50			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured
	Ki			Not Active		Inhibition < 50% @ 10 uM and thus dose-reponse curve not measured

514-36-3 靶点实验数据