HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL692366

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pD2	=	7.46
pD2	=	6.75

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL692365

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pD2	=	8.91
pD2	=	8.74

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Rattus norvegicus

External ID: CHEMBL791404

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 8
First Page: 1512
Last Page: 1515
DOI: 10.1021/jm00391a041

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Relative activity	=	0.076
Relative activity	=	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Rattus norvegicus

External ID: CHEMBL882830

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1986
Volume: 29
Issue: 7
First Page: 1281
Last Page: 1284
DOI: 10.1021/jm00157a028

Target ChEMBL ID: CHEMBL376
ChEMBL Target Name: Rattus norvegicus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Relative potency	=	0.076
Relative potency	=	0.36

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL687292

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Intrinsic actvity	=	1
Intrinsic actvity	=	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Oryctolagus cuniculus

External ID: CHEMBL773298

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL374
ChEMBL Target Name: Oryctolagus cuniculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pD2	=	7.1
pD2	=	7.58

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Oryctolagus cuniculus

External ID: CHEMBL766488

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL374
ChEMBL Target Name: Oryctolagus cuniculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Activity	=	1
Activity	=	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL685597

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.25	ED50	=	2.5E-7	M

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL687293

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Intrinsic actvity	=	1.25
Intrinsic actvity	=	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL685564

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
RA	=	146
RA	=	100

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL883981

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
6.6	ED50	=	6.6E-6	M

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Oryctolagus cuniculus

External ID: CHEMBL774062

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL374
ChEMBL Target Name: Oryctolagus cuniculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
RA	=	33
RA	=	100

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL685565

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
RA	=	507
RA	=	100

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL683333

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1986
Volume: 29
Issue: 7
First Page: 1281
Last Page: 1284
DOI: 10.1021/jm00157a028

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Relative potency	=	0.03
Relative potency	=	0.39

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL688410

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1987
Volume: 30
Issue: 8
First Page: 1512
Last Page: 1515
DOI: 10.1021/jm00391a041

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Relative activity	=	0.3
Relative activity	=	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Oryctolagus cuniculus

External ID: CHEMBL766630

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 1982
Volume: 25
Issue: 11
First Page: 1313
Last Page: 1316
DOI: 10.1021/jm00353a008

Target ChEMBL ID: CHEMBL374
ChEMBL Target Name: Oryctolagus cuniculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.03	ED50	=	3.0E-8	M

51165-07-2 靶点实验数据