HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL2433427

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 20
First Page: 5714
Last Page: 5720
DOI: 10.1016/j.bmcl.2013.08.006

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
18.45	IC50	=	18450	nM
17.34	IC50	=	17340	nM
13.93	IC50	=	13930	nM
0.72	IC50	=	720	nM
	IC50				Not Determined
2.25	IC50	=	2250	nM
43.56	IC50	=	43560	nM
57.28	IC50	=	57280	nM
29.04	IC50	=	29040	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HeLa

External ID: CHEMBL2433426

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 20
First Page: 5714
Last Page: 5720
DOI: 10.1016/j.bmcl.2013.08.006

Target ChEMBL ID: CHEMBL399
ChEMBL Target Name: HeLa
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
27.67	IC50	=	27670	nM
21.18	IC50	=	21180	nM
22.39	IC50	=	22390	nM
	IC50				Not Determined
0.85	IC50	=	850	nM
7.56	IC50	=	7560	nM
80	IC50	>	80000	nM
80	IC50	>	80000	nM
80	IC50	>	80000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HepG2

External ID: CHEMBL2433430

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 20
First Page: 5714
Last Page: 5720
DOI: 10.1016/j.bmcl.2013.08.006

Target ChEMBL ID: CHEMBL395
ChEMBL Target Name: HepG2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
19.12	IC50	=	19120	nM
16.34	IC50	=	16340	nM
12.09	IC50	=	12090	nM
	IC50				Not Determined
0.41	IC50	=	410	nM
5.23	IC50	=	5230	nM
80	IC50	>	80000	nM
35.72	IC50	=	35720	nM
80	IC50	>	80000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HL-60

External ID: CHEMBL2433429

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 20
First Page: 5714
Last Page: 5720
DOI: 10.1016/j.bmcl.2013.08.006

Target ChEMBL ID: CHEMBL383
ChEMBL Target Name: HL-60
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
14.52	IC50	=	14520	nM
11.78	IC50	=	11780	nM
10.78	IC50	=	10780	nM
	IC50				Not Determined
0.31	IC50	=	310	nM
2.37	IC50	=	2370	nM
80	IC50	>	80000	nM
38.64	IC50	=	38640	nM
80	IC50	>	80000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HL-60

External ID: CHEMBL978290

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2006
Volume: 69
Issue: 5
First Page: 807
Last Page: 810
DOI: 10.1021/np050371z

Target ChEMBL ID: CHEMBL383
ChEMBL Target Name: HL-60
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	<	10	%
Activity	<	10	%
Activity	<	10	%
Activity	<	10	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL2433428

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2013
Volume: 23
Issue: 20
First Page: 5714
Last Page: 5720
DOI: 10.1016/j.bmcl.2013.08.006

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
29.71	IC50	=	29710	nM
12.29	IC50	=	12290	nM
26.13	IC50	=	26130	nM
	IC50				Not Determined
0.73	IC50	=	730	nM
8.32	IC50	=	8320	nM
80	IC50	>	80000	nM
53.14	IC50	=	53140	nM
80	IC50	>	80000	nM

511-77-3 靶点实验数据