HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HT-29

External ID: CHEMBL2214240

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2113
Last Page: 2120
DOI: 10.1021/np3005425

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
2.3	IC50	=	2300	nM
10	IC50	>	10000	nM
1.2	IC50	=	1200	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL2214241

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2113
Last Page: 2120
DOI: 10.1021/np3005425

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
13	IC50	=	13000	nM
10	IC50	>	10000	nM
1.1	IC50	=	1100	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Jurkat

External ID: CHEMBL5589474

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL397
ChEMBL Target Name: Jurkat
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	5	%
Activity	=	18	%
Activity	=	91	%
Activity	=	132	%
Activity	=	93	%
Activity	=	23	%
Activity	=	98	%
Activity	=	100	%
Activity	=	102	%
Activity	=	111	%
Activity	=	109	%
Activity	=	52	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：MOLT-4

External ID: CHEMBL5589475

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL614177
ChEMBL Target Name: MOLT-4
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	9	%
Activity	=	6	%
Activity	=	92	%
Activity	=	119	%
Activity	=	95	%
Activity	=	11	%
Activity	=	103	%
Activity	=	100	%
Activity	=	105	%
Activity	=	101	%
Activity	=	103	%
Activity	=	32	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HL-60

External ID: CHEMBL2214244

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2113
Last Page: 2120
DOI: 10.1021/np3005425

Target ChEMBL ID: CHEMBL383
ChEMBL Target Name: HL-60
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
0.81	IC50	=	810	nM
10	IC50	>	10000	nM
0.91	IC50	=	910	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL5589476

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	27	%
Activity	=	33	%
Activity	=	80	%
Activity	=	113	%
Activity	=	83	%
Activity	=	38	%
Activity	=	93	%
Activity	=	109	%
Activity	=	96	%
Activity	=	113	%
Activity	=	104	%
Activity	=	60	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HT-29

External ID: CHEMBL5589477

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	5	%
Activity	=	5	%
Activity	=	84	%
Activity	=	107	%
Activity	=	57	%
Activity	=	7	%
Activity	=	64	%
Activity	=	106	%
Activity	=	83	%
Activity	=	108	%
Activity	=	114	%
Activity	=	71	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Acetylcholinesterase

External ID: CHEMBL1227598

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2010
Volume: 20
Issue: 17
First Page: 5290
Last Page: 5294
DOI: 10.1016/j.bmcl.2010.06.130

Target ChEMBL ID: CHEMBL220
ChEMBL Target Name: Acetylcholinesterase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Activity Comment
Ki	Not Active
Ki	Not Active
Ki	Not Active
Ki	Not Active
Ki	Not Active
Ki	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HepG2

External ID: CHEMBL2214242

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2113
Last Page: 2120
DOI: 10.1021/np3005425

Target ChEMBL ID: CHEMBL395
ChEMBL Target Name: HepG2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
1.4	IC50	=	1400	nM
10	IC50	>	10000	nM
1.5	IC50	=	1500	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：PANC-1

External ID: CHEMBL5589478

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL614139
ChEMBL Target Name: PANC-1
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	36	%
Activity	=	37	%
Activity	=	84	%
Activity	=	119	%
Activity	=	76	%
Activity	=	38	%
Activity	=	97	%
Activity	=	92	%
Activity	=	102	%
Activity	=	102	%
Activity	=	109	%
Activity	=	77	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：K562

External ID: CHEMBL2214243

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2113
Last Page: 2120
DOI: 10.1021/np3005425

Target ChEMBL ID: CHEMBL385
ChEMBL Target Name: K562
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
0.7	IC50	=	700	nM
10	IC50	>	10000	nM
1	IC50	=	1000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：B16-F10

External ID: CHEMBL1177583

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2010
Volume: 73
Issue: 7
First Page: 1223
Last Page: 1227
DOI: 10.1021/np9008255

Target ChEMBL ID: CHEMBL612656
ChEMBL Target Name: B16-F10
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
10	IC50	>	10000	nM
6.7	IC50	=	6700	nM
6.8	IC50	=	6800	nM
3.1	IC50	=	3100	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A2780

External ID: CHEMBL5589479

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL614004
ChEMBL Target Name: A2780
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	39	%
Activity	=	38	%
Activity	=	98	%
Activity	=	141	%
Activity	=	101	%
Activity	=	52	%
Activity	=	113	%
Activity	=	94	%
Activity	=	92	%
Activity	=	101	%
Activity	=	99	%
Activity	=	55	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：SK-MEL

External ID: CHEMBL1177582

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2010
Volume: 73
Issue: 7
First Page: 1223
Last Page: 1227
DOI: 10.1021/np9008255

Target ChEMBL ID: CHEMBL614914
ChEMBL Target Name: SK-MEL
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
10	IC50	>	10000	nM
8.3	IC50	=	8300	nM
8.5	IC50	=	8500	nM
4.2	IC50	=	4200	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HeLa

External ID: CHEMBL5589480

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL399
ChEMBL Target Name: HeLa
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	15	%
Activity	=	16	%
Activity	=	100	%
Activity	=	98	%
Activity	=	84	%
Activity	=	25	%
Activity	=	93	%
Activity	=	96	%
Activity	=	82	%
Activity	=	123	%
Activity	=	116	%
Activity	=	75	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL1177581

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2010
Volume: 73
Issue: 7
First Page: 1223
Last Page: 1227
DOI: 10.1021/np9008255

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
10	IC50	>	10000	nM
7.2	IC50	=	7200	nM
7.7	IC50	=	7700	nM
3.8	IC50	=	3800	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：MCF7

External ID: CHEMBL5589481

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL387
ChEMBL Target Name: MCF7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	27	%
Activity	=	17	%
Activity	=	79	%
Activity	=	131	%
Activity	=	94	%
Activity	=	24	%
Activity	=	114	%
Activity	=	102	%
Activity	=	101	%
Activity	=	103	%
Activity	=	104	%
Activity	=	49	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL1177580

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2010
Volume: 73
Issue: 7
First Page: 1223
Last Page: 1227
DOI: 10.1021/np9008255

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
10	IC50	>	10000	nM
8.2	IC50	=	8200	nM
7	IC50	=	7000	nM
4.3	IC50	=	4300	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：SAOS-2

External ID: CHEMBL5589482

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL614894
ChEMBL Target Name: SAOS-2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	27	%
Activity	=	34	%
Activity	=	79	%
Activity	=	95	%
Activity	=	92	%
Activity	=	35	%
Activity	=	97	%
Activity	=	103	%
Activity	=	97	%
Activity	=	101	%
Activity	=	98	%
Activity	=	76	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Plasmodium falciparum

External ID: CHEMBL1177464

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2009
Volume: 17
Issue: 9
First Page: 3229
Last Page: 3256
DOI: 10.1016/j.bmc.2009.02.050

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
	EC50	=	9.5E-4	ug.mL-1
	IC50	=	5.42	ug.mL-1
	IC50	=	6.6	ug.mL-1
	IC50	=	0.0015	ug.mL-1
1	IC50	<	1000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL1177579

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2010
Volume: 73
Issue: 7
First Page: 1223
Last Page: 1227
DOI: 10.1021/np9008255

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
78	IC50	=	78000	nM
10	IC50	>	10000	nM
6.7	IC50	=	6700	nM
6.8	IC50	=	6800	nM
3.7	IC50	=	3700	nM
86	IC50	=	86000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：MRC5

External ID: CHEMBL5589483

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2024
Volume: 87
Issue: 9
First Page: 2317
Last Page: 2326
DOI: 10.1021/acs.jnatprod.4c00825

Target ChEMBL ID: CHEMBL614181
ChEMBL Target Name: MRC5
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity	=	25	%
Activity	=	32	%
Activity	=	83	%
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity	=	93	%
Activity				Not Determined
Activity	=	101	%
Activity	=	96	%
Activity	=	82	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL1177578

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2010
Volume: 73
Issue: 7
First Page: 1223
Last Page: 1227
DOI: 10.1021/np9008255

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	IC50	>	10000	nM
10	IC50	>	10000	nM
7.2	IC50	=	7200	nM
4.5	IC50	=	4500	nM
4	IC50	=	4000	nM
10	IC50	>	10000	nM
10	IC50	>	10000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Trichomonas vaginalis

External ID: CHEMBL4376351

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2019
Volume: 29
Issue: 20
First Page: 126642
Last Page: 126642
DOI: 10.1016/j.bmcl.2019.126642

Target ChEMBL ID: CHEMBL612884
ChEMBL Target Name: Trichomonas vaginalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	20	%
Activity	=	15	%
Activity	=	13	%
Activity	=	35	%
Activity	=	38	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HT

External ID: CHEMBL963494

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL2366130
ChEMBL Target Name: HT
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	11.8	ug ml-1
ED50	=	4.7	ug ml-1
ED50	=	1.6	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Col2

External ID: CHEMBL963493

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL614462
ChEMBL Target Name: Col2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	5	ug ml-1
ED50	=	7.8	ug ml-1
ED50	=	6	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL963496

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	>	20	ug ml-1
ED50	>	20	ug ml-1
ED50	=	8.4	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：KB

External ID: CHEMBL963495

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL398
ChEMBL Target Name: KB
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	7.3	ug ml-1
ED50	>	20	ug ml-1
ED50	=	3.6	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL963492

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	>	20	ug ml-1
ED50	>	20	ug ml-1
ED50	>	20	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A-431

External ID: CHEMBL963491

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL614069
ChEMBL Target Name: A-431
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	11.1	ug ml-1
ED50	=	6.3	ug ml-1
ED50	=	3	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：P388

External ID: CHEMBL963501

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL389
ChEMBL Target Name: P388
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	1	ug ml-1
ED50	=	4	ug ml-1
ED50	=	0.4	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Lu1

External ID: CHEMBL963498

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL613290
ChEMBL Target Name: Lu1
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	11.1	ug ml-1
ED50	=	5.2	ug ml-1
ED50	=	2.1	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：LNCaP

External ID: CHEMBL963497

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL612518
ChEMBL Target Name: LNCaP
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	5.9	ug ml-1
ED50	=	1.8	ug ml-1
ED50	=	0.7	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：ZR-75-1

External ID: CHEMBL963500

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL614393
ChEMBL Target Name: ZR-75-1
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	6.9	ug ml-1
ED50	=	7.3	ug ml-1
ED50	=	2.6	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：SK-MEL-2

External ID: CHEMBL963499

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1993
Volume: 56
Issue: 8
First Page: 1423
Last Page: 1425
DOI: 10.1021/np50098a030

Target ChEMBL ID: CHEMBL614917
ChEMBL Target Name: SK-MEL-2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	12.9	ug ml-1
ED50	>	20	ug ml-1
ED50	=	1.9	ug ml-1

507-79-9 靶点实验数据