HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055469

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	7.55

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055470

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	6.98

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055471

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	6.66

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3054983

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	6.48

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3054984

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	6.02

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3054985

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	5.68

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3054986

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	5.14

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055491

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	4.94

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055492

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
pH	=	4.65

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055494

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Glucosyltransferase-SI

External ID: CHEMBL3055495

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL2366466
ChEMBL Target Name: Glucosyltransferase-SI
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	50	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055496

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	20.15	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055497

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	48.42	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055498

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cortical neurone

External ID: CHEMBL3107155

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2014
Volume: 24
Issue: 2
First Page: 604
Last Page: 608
DOI: 10.1016/j.bmcl.2013.12.008

Target ChEMBL ID: CHEMBL5314313
ChEMBL Target Name: Cortical neurone
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055499

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	50	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055500

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	61.29	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055501

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055502

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	50	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055503

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	60	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3055504

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Dose-dependent effect

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Streptococcus mutans

External ID: CHEMBL3053551

Protocol: N/A

Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 7
First Page: 1411
Last Page: 1417
DOI: 10.1007/s00044-011-9658-5

Target ChEMBL ID: CHEMBL612426
ChEMBL Target Name: Streptococcus mutans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	80	ug.mL-1

506-48-9 靶点实验数据