HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cytochrome P450 1A2

External ID: CHEMBL830921

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2005
Volume: 48
Issue: 11
First Page: 3808
Last Page: 3815
DOI: 10.1021/jm0489713

Target ChEMBL ID: CHEMBL3356
ChEMBL Target Name: Cytochrome P450 1A2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
370	IC50	=	370000	nM	Outside typical range
700	IC50	=	700000	nM	Outside typical range
260	IC50	=	260000	nM	Outside typical range
14	IC50	=	14000	nM
3.2	IC50	=	3200	nM
270	IC50	=	270000	nM	Outside typical range
4.4	IC50	=	4400	nM
5.5	IC50	=	5500	nM
3700	IC50	=	3700000	nM	Outside typical range
7.5	IC50	=	7500	nM
7.9	IC50	=	7900	nM
2.3	IC50	=	2300	nM
2.4	IC50	=	2400	nM
110	IC50	=	110000	nM	Outside typical range
120	IC50	=	120000	nM	Outside typical range
230	IC50	=	230000	nM	Outside typical range
45	IC50	=	45000	nM
55	IC50	=	55000	nM
3.6	IC50	=	3600	nM
15000	IC50	=	15000000	nM	Outside typical range

496-16-2 靶点实验数据