HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Adenosine kinase

External ID: CHEMBL642225

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2000
Volume: 43
Issue: 15
First Page: 2883
Last Page: 2893
DOI: 10.1021/jm000024g

Target ChEMBL ID: CHEMBL3589
ChEMBL Target Name: Adenosine kinase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.009	IC50	=	9	nM
1.2	IC50	=	1200	nM
1.0E-4	IC50	=	0.1	nM
13	IC50	=	13000	nM
0.45	IC50	=	450	nM
0.024	IC50	=	24	nM
0.035	IC50	=	35	nM
0.31	IC50	=	310	nM
1	IC50	=	1000	nM
1	IC50	=	1000	nM
1.35	IC50	=	1350	nM
0.1	IC50	=	100	nM
0.009	IC50	=	9	nM
0.026	IC50	=	26	nM
0.04	IC50	=	40	nM
6.5	IC50	=	6500	nM
0.47	IC50	=	470	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Adenosine kinase

External ID: CHEMBL969249

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2008
Volume: 16
Issue: 9
First Page: 5103
Last Page: 5108
DOI: 10.1016/j.bmc.2008.03.027

Target ChEMBL ID: CHEMBL3589
ChEMBL Target Name: Adenosine kinase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Standard Relation	Standard Value
log(10'3/IC50)	=	3.92
log(10'3/IC50)	=	5.05
log(10'3/IC50)	=	2.92
log(10'3/IC50)	=	1.89
log(10'3/IC50)	=	3.68
log(10'3/IC50)	=	6.7
log(10'3/IC50)	=	4.46
log(10'3/IC50)	=	3.51
log(10'3/IC50)	=	6.22
log(10'3/IC50)	=	1.78
log(10'3/IC50)	=	3
log(10'3/IC50)	=	2.87
log(10'3/IC50)	=	4.59
log(10'3/IC50)	=	4.4
log(10'3/IC50)	=	2.92
log(10'3/IC50)	=	3.33
log(10'3/IC50)	=	3.51

49554-55-4 靶点实验数据