HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HT-29

External ID: CHEMBL4119185

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2017
Volume: 80
Issue: 5
First Page: 1397
Last Page: 1403
DOI: 10.1021/acs.jnatprod.6b01069

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
6.4	IC50	=	6400	nM
14.1	IC50	=	14100	nM
20	IC50	>	20000	nM
0.0014	IC50	=	1.4	nM
20	IC50	>	20000	nM
20	IC50	>	20000	nM
20	IC50	>	20000	nM
20	IC50	>	20000	nM
	IC50				Not Determined
	IC50				Not Determined
	IC50				Not Determined
20	IC50	>	20000	nM
	IC50				Not Determined
20	IC50	>	20000	nM
	IC50				Not Determined
	IC50				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：MCF7

External ID: CHEMBL4119184

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2017
Volume: 80
Issue: 5
First Page: 1397
Last Page: 1403
DOI: 10.1021/acs.jnatprod.6b01069

Target ChEMBL ID: CHEMBL387
ChEMBL Target Name: MCF7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
17.1	IC50	=	17100	nM
5.7	IC50	=	5700	nM
20	IC50	>	20000	nM
	IC50				Not Determined
20	IC50	>	20000	nM
20	IC50	>	20000	nM
20	IC50	>	20000	nM
20	IC50	>	20000	nM
	IC50				Not Determined
9.7	IC50	=	9700	nM
	IC50				Not Determined
20	IC50	>	20000	nM
14.9	IC50	=	14900	nM
20	IC50	>	20000	nM
20	IC50	>	20000	nM
20	IC50	>	20000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Leishmania donovani

External ID: CHEMBL3371121

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2014
Volume: 77
Issue: 9
First Page: 1987
Last Page: 1991
DOI: 10.1021/np5000473

Target ChEMBL ID: CHEMBL367
ChEMBL Target Name: Leishmania donovani
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.4	IC90	=	400	nM
9.2	IC50	=	9200	nM
12.4	IC90	=	12400	nM
3.3	IC50	=	3300	nM
6.1	IC90	=	6100	nM
8.5	IC50	=	8500	nM
10.4	IC90	=	10400	nM
13	IC50	=	13000	nM
22	IC90	=	22000	nM
6.9	IC50	=	6900	nM
61	IC90	=	61000	nM
34	IC50	=	34000	nM

495-08-9 靶点实验数据